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peptidylglycine monooxygenase

forms alpha-amide from C-terminal glycine precursor of peptide hormones by oxidation of hydrogen & spontaneous hydrolysis of resulting imino linkage; posseses both an alpha-hydroxylation domain (PHM) and an alpha-amidation domain (PAL); PAM refers to the bifunctional enzyme; may be the same as bovine Somatotropin; RefSeq NM_013626 (mouse), NM_013000 (rat), NM_138822 (human)
Also Known As:
AE-II protein, Xenopus; Pam protein, mouse; Pam protein, rat; SP-GLYE protein, human; alpha-amidating enzyme AE-II; alpha-amidation monooxygenase; peptide C-terminal alpha-amidating enzyme II, Xenopus; peptidyl alpha-amidating monooxygenase; peptidyl-glycine alpha-amidating monooxygenase; peptidylglycine 2-hydroxylase; peptidylglycine alpha-amidating monooxygenase; peptidylglycine alpha-amidating monooxygenase, mouse; peptidylglycine alpha-amidating monooxygenase, rat; peptidylglycine alpha-hydroxylating monooxygenase; peptidylglycine hydroxylase; substance P-Gly12 protein, human
Networked: 17 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ouafik, L'Houcine: 2 articles (12/2007 - 04/2002)
2. Green, George R: 1 article (08/2015)
3. Burns, Timothy J: 1 article (08/2015)
4. Ali, Amna: 1 article (08/2015)
5. May, Sheldon W: 1 article (08/2015)
6. Lucrezi, Jacob D: 1 article (08/2015)
7. Matesic, Diane F: 1 article (08/2015)
8. Pierre, Sébastien: 1 article (09/2010)
9. Giorgi, Michel: 1 article (09/2010)
10. Réglier, Marius: 1 article (09/2010)

Related Diseases

1. Carcinoma (Carcinomatosis)
2. Neoplasms (Cancer)
3. Glioblastoma (Glioblastoma Multiforme)
4. Thyroid Neoplasms (Thyroid Cancer)
5. Seizures (Seizure)

Related Drugs and Biologics

1. Peptides
2. Copper
3. Adrenomedullin
4. Chromogranin A
5. Carboxypeptidase B
6. Carboxypeptidase H (Carboxypeptidase E)
7. Peptide Hormones (Polypeptide Hormones)
8. Complementary DNA (cDNA)
9. Reactive Oxygen Species (Oxygen Radicals)
10. Messenger RNA (mRNA)