dopaquinone

01/01/1987 - "Dopaquinone addition products in cultured human melanoma cells."
01/01/1998 - "Generalized melanosis in metastatic malignant melanoma: the possible role of DOPAquinone metabolites."
06/01/1996 - "Our data clearly indicate that 5-S-CD is formed in human melanoma cells by a tyrosinase-dependent mechanism involving the addition of CysH to dopaquinone. "
01/01/1998 - "The deposition of DOPAquinone metabolites secreted by the melanoma cells may contribute to the unusual melanin deposition within collagen bundles in the affected dermis."
12/06/1990 - "These results suggest that selective TU incorporation in pigmented melanomas and other melanin-producing systems is due to the covalent binding to dopaquinone, produced by tyrosinase catalyzed oxidation of tyrosine."

01/01/2017 - "The enzyme tyrosinase regulates melanogenesis and skin hyperpigmentation by converting L-3,4-dihydroxyphenylalanine (L-DOPA) into dopaquinone, a key step in the melanin biosynthesis. "
01/12/2006 - "Tyrosinase is a copper-dependent enzyme which converts l- tyrosine to dopaquinone and is involved in different biological processes such as melanogenesis and skin hyperpigmentation. "

01/01/1981 - "5-S-Cysteinyldopa, an amino acid formed by nucleophilic addition of cysteine to dopaquinone, has been detected in the ganglion stellatum of the cow in amounts varying between 21 and 35 ng/g ganglionic tissue. "

01/01/1998 - "Generalized melanosis in metastatic malignant melanoma: the possible role of DOPAquinone metabolites."

01/01/2021 - "Melanin synthesis starts via the hydroxylation of L-tyrosine to L-3,4-Dihydroxyphenylalanine (DOPA) catalyzed by the enzyme known as Tyrosinase (TYR), which triggers further conversion reaction to DOPAquinone and then to DOPAchrome. "