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5-benzylacyclouridine

structure given in first source

Also Known As:

5-BACU; 5-benzyl-1-(2'-hydroxyethoxymethyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-(phenylmethyl)-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        5-benzylacyclouridine: 3

Related Diseases

1.	Neoplasms (Cancer) 12/01/1998 - "Clinical samples of human tumors and adjacent normal tissues were assayed for phosphorolytic activity and sensitivity to 5-benzylacyclouridine (BAU), a potent inhibitor of the enzyme presently in Phase I-II clinical trial. " 12/01/1997 - "A uridine phosphorylase inhibitor, 5-benzylacyclouridine (BAU), has been utilized as biochemical modulator of 5-fluorouracil (5-FU) anti-tumor activity in a murine tumor model. " 12/01/1997 - "19F NMR monitoring of in vivo tumor metabolism after biochemical modulation of 5-fluorouracil by the uridine phosphorylase inhibitor 5-benzylacyclouridine."
2.	Lymphoma (Lymphomas) 09/01/1984 - "Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine."

Related Drugs and Biologics

1.	Uridine Phosphorylase
2.	Nucleosides
3.	Fluorouracil (Carac)
4.	Enzymes
5.	5-benzyloxybenzylacyclouridine