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propionamide

Networked: 20 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - propionamide: 20

Experts

1.	Stein, Christoph: 2 articles (01/2022 - 11/2018)
2.	Bok, Diana Daeun: 1 article (01/2022)
3.	Bunnett, Nigel W: 1 article (01/2022)
4.	Degro, Claudius: 1 article (01/2022)
5.	Guzman-Rodriguez, Mabel: 1 article (01/2022)
6.	Jaramillo-Polanco, Josue O: 1 article (01/2022)
7.	Jensen, Dane D: 1 article (01/2022)
8.	Jiménez-Vargas, Nestor Nivardo: 1 article (01/2022)
9.	Latorre, Rocco: 1 article (01/2022)
10.	Lomax, Alan Edward: 1 article (01/2022)

Related Diseases

1.	Ulcerative Colitis 11/01/2023 - "N -(3-fluoro-1-phenethylpiperidine-4-yl)- N -phenyl propionamide could provide safe and effective analgesia during acute colitis, such as flares of ulcerative colitis."
2.	Colitis 11/01/2023 - "N -(3-fluoro-1-phenethylpiperidine-4-yl)- N -phenyl propionamide could provide safe and effective analgesia during acute colitis, such as flares of ulcerative colitis." 11/01/2023 - "We studied the analgesic efficacy and side-effect profile of a pH-sensitive fentanyl analog, (±)- N -(3-fluoro-1-phenethylpiperidine-4-yl)- N -phenyl propionamide (NFEPP), during the evolution of colitis induced in mice with dextran sulphate sodium. "
3.	Pain (Aches) 01/01/2021 - "Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain." 01/01/2022 - "We investigated whether a fentanyl analogue, (±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide (NFEPP), which preferentially activates MOPr in acidified diseased tissues, would inhibit pain in a preclinical model of inflammatory bowel disease (IBD) without side effects in healthy tissues. " 01/01/2023 - "N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide is a newly-designed pain killer selectively activating G-protein-coupled mu-opioid receptors (MOR) in acidic injured tissues, and therefore devoid of central side effects which are typically elicited at normal pH values in healthy tissues. "
4.	Neoplasms (Cancer) 01/01/2019 - "The inhibitory effects on tumor growth were evaluated and it was observed that N-(2,5-dichlorophenyl)-2-(4-isobutylphenyl) propionamide (4e) and N-(2-chlorophenyl)-2-(4-isobutylphenyl) propionamide (4g) exhibited excellent antitumor activity compared to all other derivatives. " 01/07/2014 - "Furthermore, when a mouse xenograft model of prostate cancer was treated with the γ-secretase inhibitor DBZ {(2S)-2-[2-(3,5-difluorophenyl)-acetylamino]-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-propionamide}, generation of TβRI-ICD was prevented, transcription of the gene encoding the proinvasive transcription factor Snail1 was reduced, and tumor growth was inhibited. "
5.	Infections 10/01/2010 - "The γ-secretase inhibitor (S,S)-2-[2-(3,5-difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide (compound XXI) inhibits infection in vitro by all types of papillomavirus pseudovirions tested, with a 50% inhibitory concentration (IC(50)) of 130 to 1,000 pM, regardless of reporter construct and without impacting cellular viability. " 01/01/1994 - "Of 4 amides, only semicarbazide vaccine conferred complete mucosal defense, while acetamide, propionamide, and isonicotinic acid hydrazide vaccines lead to regional infection. "

Related Drugs and Biologics

1.	Amyloid Precursor Protein Secretases (beta-Secretase)
2.	Small Interfering RNA (siRNA)
3.	mu Opioid Receptors (mu Opioid Receptor)
4.	Sodium
5.	Opioid Receptors (Opioid Receptor)
6.	Fentanyl (Sublimaze)
7.	acetamide
8.	DNA-Activated Protein Kinase
9.	5-HT1A Serotonin Receptor
10.	5-HT1 Serotonin Receptors

Related Therapies and Procedures

1.	Analgesia