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cystine dimethyl ester

RN given refers to (L)-isomer

Also Known As:

dimethyl-L-cystine

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kessler, Adriana: 2 articles (01/2018 - 05/2008)
2.	Athaydes, Genaro A: 1 article (01/2018)
3.	Feksa, Luciane R: 1 article (01/2018)
4.	Figueiredo, Vandré C: 1 article (01/2018)
5.	Franceschi, Itiane D DE: 1 article (01/2018)
6.	Mezzomo, Nathana J: 1 article (01/2018)
7.	Rech, Virginia C: 1 article (01/2018)
8.	Wannmacher, Clovis M D: 1 article (01/2018)
9.	Abdel Mageed, Asim B: 1 article (01/2015)
10.	Baykal, Asli: 1 article (01/2015)

Related Diseases

1.	Cystinosis 06/01/1985 - "Prenatal diagnosis of cystinosis upon exposure of amniotic cells to cystine dimethyl ester." 06/17/1982 - "Heterozygote detection in cystinosis, using leukocytes exposed to cystine dimethyl ester." 09/01/2005 - "Altered mitochondrial oxidative phosphorylation has been demonstrated in animal proximal tubules loaded with cystine dimethyl ester, mimicking cystine accumulation in cystinosis, but has not been confirmed in cells of patients with cystinosis. "
2.	Body Weight (Weight, Body) 01/01/2018 - "Animals were injected twice a day with 1.6 µmol/g body weight cystine dimethyl ester and/or 0.26 µmol/g body weight cysteamine from the 16th to the 20th postpartum day and euthanized after 12 hours. " 05/01/2008 - "Animals were injected with 1.6 micromol/g cystine dimethyl ester and/or 0.26 micromol/g body weight cysteamine. "
3.	Respiratory Insufficiency (Respiratory Failure) 11/05/2023 - "In rodents and dogs, the esterified D-CSNO precursor-d-cystine dimethyl ester (ATLX-0199)-overcomes opioid- and benzodiazepine-induced respiratory depression while maintaining analgesia. "
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2015 - "Cystine dimethyl ester induces apoptosis through regulation of PKC-δ and PKC-ε in prostate cancer cells." 01/01/2015 - "We investigated oxidative regulatory responses of PKC-δ and PKC-ε to cystine dimethyl ester (CDME), a metabolic precursor of cystine, which, by inducing release of cellular cystine stimulates apoptosis in different prostate cancer cells, PC3 and LNCaP, compared to normal RWPE1 cells. "
5.	Mucolipidoses (Sialidosis) 01/01/1984 - "To unravel the question whether the same clearance defect or two different mechanisms cause cystine accumulation in I-cell disease, we used the cystine loading technique upon exposure of skin fibroblasts to radioactive cystine dimethyl ester. "

Related Drugs and Biologics

1.	Cystine (L-Cystine)
2.	Cysteamine (Mercaptamine)
3.	Benzodiazepines
4.	Opioid Analgesics (Opioids)

Related Therapies and Procedures

1.	Analgesia