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cadeguomycin
from Streptomyces hygroscopicus; structure given in first source
Also Known As:
2-amino-3,4-dihydro-4-oxo-7-beta-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carboxylic acid; 7-carboxy-7-deazaguanosine; 1H-Pyrrolo(2,3-d)pyrimidine-5-carboxylic acid, 2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Guanosine: 1156
cadeguomycin: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Guanosine: 1156
cadeguomycin: 3
Ribonucleosides: 49
Guanosine: 1156
cadeguomycin: 3
Related Diseases
1.
Carcinoma (Carcinomatosis)
04/01/1983 - "
Cadeguomycin shows low acute toxicity in mice, enhances DTH reaction, and inhibits Ehrlich ascitic carcinoma in mice.
"
05/01/1985 - "
Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice.
"
2.
Lewis Lung Carcinoma
05/01/1985 - "
Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice.
"
3.
Neoplasms (Cancer)
05/01/1985 - "
The results suggest that cadeguomycin inhibits tumor growth and metastasis in association with modification of the immune system.
"
4.
Neoplasm Metastasis (Metastasis)
05/01/1985 - "
The results suggest that cadeguomycin inhibits tumor growth and metastasis in association with modification of the immune system.
"
05/01/1985 - "
Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice.
"
05/01/1985 - "
The combined administration of arabinosylcytosine and cadeguomycin displayed potentiation in the inhibition of growth of ip-implanted P388 leukemia and metastasis of sc-implanted P388 leukemia to the regional lymph nodes.
"
5.
Lymphoma (Lymphomas)
02/01/1987 - "
The treatment of K562 human myeloblastic leukemia cells and YAC-1 murine lymphoma cells with cadeguomycin at concentrations over 0.6 microM significantly enhanced the cytotoxicity of 1-beta-D-arabinofuranosylcytosine (ara-C).
"
Related Drugs and Biologics
1.
Cytarabine (Cytosar-U)