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ecgonine methyl ester

major metabolite of cocaine; RN given refers to parent cpd (1R-(exo,exo))-isomer
Also Known As:
ecgonine methyl ester hydrochloride, (1R-(exo,exo))-isomer; ecgonine methyl ester, (1R-(2-endo,3-exo))-isomer; ecgonine methyl ester, (1R-(2-exo,3-endo))-isomer; ecgonine methyl ester, (1R-(endo,endo))-isomer; ecgonine methyl ester, (1S-(endo,endo))-isomer; methyl ecgonine
Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Bermejo-Barrera, Pilar: 2 articles (06/2016 - 03/2016)
2. Moreda-Piñeiro, Antonio: 2 articles (06/2016 - 03/2016)
3. Sánchez-González, Juan: 2 articles (06/2016 - 03/2016)
4. Tabernero, María Jesús: 2 articles (06/2016 - 03/2016)
5. Cabarcos, Pamela: 1 article (06/2016)
6. García-Carballal, Sara: 1 article (06/2016)
7. Bermejo, Ana María: 1 article (03/2016)
8. Chantada-Vázquez, María Pilar: 1 article (03/2016)
9. Peña-Vázquez, Elena: 1 article (03/2016)
10. Moody, David E: 1 article (03/2004)

Related Diseases

1. Cocaine-Related Disorders (Cocaine Addiction)
03/01/2016 - "Simple and low cost methods have therefore been optimized for assessing cocaine abuse in urine by monitoring the fluorescence quenching when the template (COC) and also metabolites from COC [benzoylecgonine (BZE) and ecgonine methyl ester (EME)] are present. "
06/03/1994 - "In the later stages after intake, the important markers of cocaine abuse are its main metabolites in urine, benzoylecgonine and ecgonine methyl ester. "
03/01/2004 - "We used 878 sweat patches worn by 38 subjects receiving treatment for cocaine dependence to compare analysis of the extracts of the patches for cocaine immuno-equivalents by radioimmunoassay (RIA) with determination of cocaine, benzoylecgonine (BE), and ecgonine methyl ester (EME) by GC-MS. Preliminary validation experiments demonstrate that the GC-MS method using positive ion chemical ionization had sufficient specificity and recovery to support a lower limit of quantitation (LLOQ) of 4 ng/patch and was precise and accurate across a linear range up to 500 ng/patch. "
03/01/1994 - "The psychostimulant drug of abuse, cocaine (benzoylecgonine methyl ester), is rapidly metabolized by cleavage of its two ester groups, to give benzoylecgonine (BE) and ecgonine methyl ester, and by N-demethylation, to give N-norcocaine (NC). "
06/17/2016 - "A selective molecularly imprinted polymer synthesized for the selective retention of cocaine (COC) and its metabolites [benzoylecgonine (BZE), ecgonine methyl ester (EME), and cocaethylene (CE)] was used as a solid adsorbent for assessing cocaine abuse by plasma analysis. "
2. Substance-Related Disorders (Drug Abuse)
3. Hepatocellular Carcinoma (Hepatoma)
4. Body Weight (Weight, Body)

Related Drugs and Biologics

1. benzoylecgonine
2. Cocaine (Cocaine HCl)
3. cocaethylene
4. Opiate Alkaloids
5. N-Methyl-3,4-methylenedioxyamphetamine (MDMA)
6. Illicit Drugs (Recreational Drugs)
7. Morphine (MS Contin)
8. Methamphetamine (Desoxyn)
9. Esters
10. Heroin (Diamorphine)