HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

bicifadine

a nonopioid analgesic that modulates the monoaminergic pathways involved in pain

Also Known As:

bicifadine hydrochloride

Networked: 5 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Bridged-Ring Heterocyclic Compounds
  - Heterocyclic Bridged Bicyclo Compounds
    - bicifadine: 5

Experts

1.	Krieter, Philip A: 3 articles (02/2008 - 06/2007)
2.	Gohdes, Mark: 2 articles (02/2008 - 02/2008)
3.	Musick, Timothy J: 2 articles (02/2008 - 02/2008)
4.	Galvin, Imelda: 1 article (09/2014)
5.	Gilron, Ian: 1 article (09/2014)
6.	Goldstein, David: 1 article (09/2014)
7.	Kalso, Eija: 1 article (09/2014)
8.	Phelan, Rachel: 1 article (09/2014)
9.	Raja, Srinivasa: 1 article (09/2014)
10.	Wong, Karen: 1 article (09/2014)

Related Diseases

1.	Postoperative Pain 04/01/1982 - "The oral analgesic efficacy of bicifadine hydrochloride in postoperative pain." 09/01/2014 - "Fifteen studies (985 participants) of early postoperative pain evaluated amitriptyline (three trials), bicifadine (two trials), desipramine (three trials), duloxetine (one trial), fluoxetine (one trial), fluradoline (one trial), tryptophan (four trials), and venlafaxine (one trial). "
2.	Acute Pain 02/01/2008 - "Bicifadine [DOV 220,075; (+/-)-1-(4-methylphenyl)-3-azabicyclo-[3.1.0]hexane HCl)] is a non-narcotic analgesic that has proven to be effective for the treatment of acute pain in clinical studies. "
3.	Chronic Pain 06/01/2007 - "These results indicate that bicifadine is a functional triple reuptake inhibitor with antinociceptive and antiallodynic activity in acute, persistent, and chronic pain models, with activation of dopaminergic pathways contributing to its antihyperalgesic actions." 06/01/2007 - "Orally administered bicifadine is an effective antinociceptive in several models of acute, persistent, and chronic pain. " 06/01/2007 - "Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain." 02/01/2008 - "Bicifadine [DOV 220,075; (+/-)-1-(4-methylphenyl)-3-azabicyclo[3.1.0]-hexane HCl)] is a non-narcotic analgesic that is effective in animal models of acute and chronic pain. "
4.	Visceral Pain 06/01/2007 - "Bicifadine potently suppressed pain responses in both the Randall-Selitto and kaolin models of acute inflammatory pain and in the phenyl-p-quinone-induced and colonic distension models of persistent visceral pain. "
5.	Pain (Aches) 06/01/2007 - "Bicifadine also normalized the nociceptive threshold in the complete Freund's adjuvant model of persistent inflammatory pain and suppressed mechanical and thermal hyperalgesia and mechanical allodynia in the spinal nerve ligation model of chronic neuropathic pain. " 06/01/2007 - "Bicifadine potently suppressed pain responses in both the Randall-Selitto and kaolin models of acute inflammatory pain and in the phenyl-p-quinone-induced and colonic distension models of persistent visceral pain. "

Related Drugs and Biologics

1.	Analgesics (Analgesic Drugs)
2.	Narcotics (Narcotic Analgesics)
3.	Hexanes
4.	Tryptophan (L-Tryptophan)
5.	Fluoxetine (Prozac)
6.	Desipramine (Pertofrane)
7.	Amitriptyline (Elavil)
8.	Venlafaxine Hydrochloride (Effexor)
9.	Duloxetine Hydrochloride (Cymbalta)
10.	fluradoline

Related Therapies and Procedures

1.	Ligation