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selenocysteine lyase

decomposes L-selenocysteine into L-alanine & H2Se

Also Known As:

csdB protein, E coli; selenocysteine beta-lyase; sufS protein, E coli; ynhB protein, E coli

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - selenocysteine lyase: 10

Experts

1.	Berry, Marla J: 6 articles (12/2020 - 10/2012)
2.	Hashimoto, Ann C: 6 articles (12/2020 - 10/2012)
3.	Seale, Lucia A: 4 articles (12/2020 - 10/2012)
4.	Torres, Daniel J: 2 articles (12/2020 - 07/2019)
5.	Watanabe, Ligia M: 2 articles (12/2020 - 10/2019)
6.	Pitts, Matthew W: 2 articles (07/2019 - 04/2014)
7.	Gilman, Christy L: 2 articles (10/2015 - 10/2012)
8.	Deng, Youping: 1 article (10/2019)
9.	Guirguis, Kyrillos: 1 article (10/2019)
10.	Ha, Herena Y: 1 article (10/2019)

Related Diseases

1.	Obesity 10/01/2015 - "Diet-induced obesity in the selenocysteine lyase knockout mouse." 12/01/2020 - "Effects of selenium supplementation on diet-induced obesity in mice with a disruption of the selenocysteine lyase gene." 07/23/2019 - "Whole-body knockout of the selenium recycling enzyme, selenocysteine lyase (Scly), increases susceptibility to metabolic syndrome and diet-induced obesity in mice. " 10/26/2019 - "Disruption of the selenocysteine lyase gene (Scly) in mice (Scly-/- or Scly KO) led to obesity with dyslipidemia, hyperinsulinemia, glucose intolerance and lipid accumulation in the hepatocytes. "
2.	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/01/2012 - "Disruption of the selenocysteine lyase-mediated selenium recycling pathway leads to metabolic syndrome in mice." 07/23/2019 - "Whole-body knockout of the selenium recycling enzyme, selenocysteine lyase (Scly), increases susceptibility to metabolic syndrome and diet-induced obesity in mice. "
3.	Dyslipidemias (Dyslipidemia) 10/26/2019 - "Disruption of the selenocysteine lyase gene (Scly) in mice (Scly-/- or Scly KO) led to obesity with dyslipidemia, hyperinsulinemia, glucose intolerance and lipid accumulation in the hepatocytes. "
4.	Decapitation 01/01/1987 - "Weanling male rats were fed a basal selenium (Se)-deficient diet or this diet plus 2 ppm Se as either selenite, selenocystine (SeCys) or selenomethionine (SeMet) for 9 wk. The rats were killed by decapitation while anesthetized with ether, and tissues were assayed for glutathione peroxidase (GPx) and selenocysteine lyase activities, and for Se content. "
5.	Glucose Intolerance 10/26/2019 - "Disruption of the selenocysteine lyase gene (Scly) in mice (Scly-/- or Scly KO) led to obesity with dyslipidemia, hyperinsulinemia, glucose intolerance and lipid accumulation in the hepatocytes. "

Related Drugs and Biologics

1.	Selenium
2.	Enzymes
3.	Selenoprotein P
4.	Selenoproteins (Selenoprotein)
5.	Selenious Acid (Selenite)
6.	Transcription Factor AP-1 (Transcription Factor AP 1)
7.	Selenocysteine
8.	Selenomethionine (Sethotope)
9.	Transfer RNA (tRNA)
10.	Messenger RNA (mRNA)