|1.||Zhang, Yan: 7 articles (01/2012 - 04/2002)|
|2.||Zhu, Lin: 6 articles (10/2015 - 01/2011)|
|3.||Zhang, Guang-Xian: 5 articles (10/2015 - 01/2011)|
|4.||Sun, Xueying: 5 articles (01/2014 - 04/2009)|
|5.||Huang, Jian: 5 articles (05/2012 - 02/2004)|
|6.||Liu, Xiao-Shan: 5 articles (05/2011 - 01/2006)|
|7.||Zhou, Min: 4 articles (10/2015 - 04/2009)|
|8.||Ma, Lingdi: 4 articles (10/2015 - 02/2008)|
|9.||Kan, Quan-Cheng: 4 articles (10/2015 - 01/2013)|
|10.||Zhou, Yuhong: 4 articles (06/2014 - 01/2012)|
05/01/2014 - "In vivo study found that matrine effectively inhibited the tumor formation of Eca-109 cells in nude mice. "
01/01/2014 - "In the in vivo study, matrine significantly attenuated tumor growth with AIF release from mitochondria into nucleus in nude mice. "
10/01/2013 - "Along with the further studies on matrine's anti-tumor mechanism, it has a broad prospect for development and application in tumor clinical treatment."
10/01/2013 - "[Advance in studies on anti-tumor mechanism of matrine]."
02/01/2012 - "More importantly our in vivo, studies showed that administration of matrine decreased tumor growth in a dose-dependent manner. "
10/01/2000 - "It can therefore be assumed that the direct action of matrine on the stomach smooth muscle possibly contributes to the mechanism of the matrine induced inhibition of the spontaneous gastric motility and rise in the tone of stomach, and may play an important role in the protection of the restraint and water immersion stress ulcer formetion."
07/01/1985 - "The administration of matrine, which has antiulcerogenic activity against stress ulcer, exhibited clear contraction on the preparation of the fundus strip of rats at high concentration (from 2 X 10(-4) g/ml). "
10/01/2000 - "In spite of its weak inhibition of gastric acid secretion, intravenous injection of matrine is rather effective for stress ulcer. "
03/01/1984 - "[Protective effects of matrine and oxymatrine on stress ulcer in relation to their effects on the central nervous system]."
10/01/2000 - "Matrine and oxymatrine, major components of Sophora flavescens, were confirmed to have a protective effect on restraint and water immersion stress ulcer in mice. "
09/01/2009 - "The aim of the study is to elucidate the protective effects of matrine on arrhythmic rat induced by myocardial infarction (MI) and further explore underlying targets. "
05/01/1991 - "These results indicated that sophoridine showed protective effects on acute myocardial infarction. "
09/01/2009 - "Knowledge of matrine from this work may provide insight into the development of new drugs for long-term myocardial infarction treatment."
05/01/1991 - "[Protective action of sophoridine on acute myocardial infarction in anesthetized dogs]."
05/01/1991 - "The effects of sophoridine on acute myocardial infarction induced by ligation of left anterior descending coronary artery in 16 anesthetized and open-chest dogs were studied. "
12/01/2014 - "The rats with heart failure exhibited a significant reduction in ejection fraction and fractional shortening, as well as an increase in the left ventricular end systolic dimension, and matrine attenuated this decline in heart function. "
12/01/2014 - "The purpose of the present study was to investigate whether matrine has a protective effect on heart failure in rats. "
12/01/2014 - "In conclusion, matrine had a preventive role in heart failure in rats at least in part by inhibiting myocardial apoptosis and the β3-AR pathway."
09/01/2015 - "It has been demonstrated that matrine exerts protective effects against heart failure by decreasing the expression of caspase-3 and Bax, and increasing Bcl‑2 levels. "
12/01/2014 - "Matrine improved the function of heart failure in rats via inhibiting apoptosis and blocking β3‑adrenoreceptor/endothelial nitric oxide synthase pathway."
|5.||Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/01/2011 - "Matrine suppresses production of IL-23/IL-17 and ameliorates experimental autoimmune encephalomyelitis."
12/01/2014 - "Upregulation of immunomodulatory molecules by matrine treatment in experimental autoimmune encephalomyelitis."
01/01/2013 - "Inhibitory effect of matrine on blood-brain barrier disruption for the treatment of experimental autoimmune encephalomyelitis."
10/01/2015 - "Matrine ameliorates experimental autoimmune encephalomyelitis by modulating chemokines and their receptors."
02/07/2014 - "Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis."
|2.||Caspase 3 (Caspase-3)
|6.||Interleukin-6 (Interleukin 6)
|9.||Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
|10.||HMGB1 Protein (HMG1)
|1.||Drug Therapy (Chemotherapy)
|4.||Heterologous Transplantation (Xenotransplantation)
|5.||Chinese Traditional Medicine (Traditional Chinese Medicine)