viprostol

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8 relevant articles (1 outcomes, 2 trials/studies) found for this Bio-Agent

Description: structure given in first source; RN given refers to (5Z,11alpha,13E)-isomer

Also Known As:

15-(deoxy)-16-hydroxy-16-vinylprostaglandin E2 methyl ester; 15-deoxy-16-hydroxy-16-vinyl-PGE2 methyl ester; CL 115,347; CL 115347; DHV-PGE2Me; viprostol, (+-)-isomer

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Hypertension (High Blood Pressure) 09/01/1983 - "The present findings suggest that CL 115,347 may be useful for the treatment of human hypertension." 06/01/1986 - "The cardiovascular responses to the chronic administration of CL 115347 were studied in a double-blind, placebo-controlled trial in 26 subjects with essential hypertension (16 given drug, 10 placebo) maintained on a 100-mEq sodium diet" 09/01/1983 - "CL 115,347 [dl-15-deoxy-16-hydroxy-16(alpha/beta)-vinyl prostaglandin E2 methyl ester] has a broad spectrum of antihypertensive activity in many animal hypertension models in every species tested" Get all the results and reference details, order at left...
2.	Ischemia 11/01/1989 - "The present study evaluated the ability of DHV-PGE2ME, a topically effective 16-vinyl prostaglandin E2 analogue, to improve the tolerance of skin flaps to a period of ischemia" Get all the results and reference details, order at left...
3.	Tachycardia (Tachyarrhythmias) 02/01/1983 - "CL 115,347 decreased vasopressor responses induced by electrical stimulation of the spinal cord at T7-T9 but did not decrease the tachycardia induced by stimulation of the cardioaccelerator segments (C7-T1) in pithed SHR" 12/01/1986 - "Viprostol did not antagonize the tachycardia induced by stimulation of the discrete segments at C7-T1 (cardio-accelerator) of the spinal cord in pithed SHR, suggesting that viprostol did not activate the presynaptic alpha-adrenoceptors" Get all the results and reference details, order at left...
4.	Ganglion Cysts (Ganglion) 12/01/1986 - "In cats, viprostol did not inhibit renal sympathetic nerve discharge (RSND) monitored at the postganglionic region, indicating that nerve transmission or conduction was not blocked at the ganglion or the pre- or postganglionic fibres" Get all the results and reference details, order at left...
5.	Stroke (Strokes) 02/01/1984 - "Effects of CL 115,347, (+/-)-15-deoxy-16-hydroxy-16-vinyl-PGE2 methyl ester, on cardiovascular responses and plasma catecholamines in pithed stroke-prone spontaneously hypertensive rats during sympathetic stimulation." 02/01/1984 - "The effect of CL 115,347, a topically active antihypertensive PGE2 analog, and PGE2 on changes in blood pressure (BP), heart rate (HR) response and plasma epinephrine (E) and norepinephrine (NE) levels induced by stimulation of the sympathetic spinal cord outflow were studied in pithed stroke-prone spontaneously hypertensive rats (SHRSP)" Get all the results and reference details, order at left...
7 Diseases and 8 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Sodium
3.	prostaglandin E2 methyl ester
4.	Dinoprost
5.	Adrenergic Receptors (Adrenergic Receptor)
6.	Norepinephrine (Noradrenaline)
7.	Epinephrine (Adrenaline)
8.	Catecholamines
8 Drugs and Important Bio-Agents and 6 more articles analyzed in the Research Interface, order at left...

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