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isocitric acid (isocitrate)

RN given refers to unlabeled parent cpd
Also Known As:
isocitrate; isocitric acid, (11)C-labeled; isocitric acid, calcium salt; isocitric acid, disodium salt; isocitric acid, potassium salt; isocitric acid, sodium salt; isocitric acid, trisodium salt
Networked: 312 relevant articles (3 outcomes, 23 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yan, Hai: 5 articles (10/2019 - 02/2009)
2. Su, Shinsan M: 5 articles (03/2014 - 09/2010)
3. French, Pim J: 4 articles (08/2019 - 01/2011)
4. Yen, Katharine E: 4 articles (01/2019 - 09/2012)
5. Guan, Kun-Liang: 4 articles (10/2018 - 04/2009)
6. Bovée, Judith V M G: 4 articles (12/2017 - 01/2013)
7. von Deimling, Andreas: 4 articles (09/2017 - 08/2010)
8. Straley, Kimberly: 4 articles (01/2017 - 05/2013)
9. Bigner, Darell D: 4 articles (12/2012 - 02/2009)
10. Delehanty, Lorrie L: 3 articles (12/2021 - 07/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Anemia
3. Glioma (Gliomas)
4. Glioblastoma (Glioblastoma Multiforme)
5. Astrocytoma (Pilocytic Astrocytoma)
01/01/2018 - "A subset of TMZ-treated, isocitrate dehydrogenase‒mutant, low-grade astrocytomas recur as more malignant tumors with thousands of de novo, coding mutations bearing a signature of TMZ-induced hypermutation. "
09/01/2015 - "To establish an accurate subclassification of low-grade gliomas, we retrospectively evaluated isocitrate dehydrogenase-1 (IDH1) mutation in clinical specimens of diffuse astrocytomas (DA) and oligodendroglial tumors separately. "
09/01/2014 - "To study the putative expression patterns and clinical significance of Hsp27, we assessed the associations between Hsp27, R132H mutation of Isocitrate dehydrogenase1 (IDH1-R132H), Hypoxia-inducible factor subunit alpha (HIF-1 alpha), Carbonic anhydrase IX (CA IX), and patient prognosis in astrocytic gliomas. "
01/01/2015 - "Recent genetic studies have revealed that the major categories of gliomas, such as circumscribe astrocytomas, infiltrating astrocytomas/oligodendrogliomas, and glioblastoma, roughly correspond to major genetic alterations, including isocitrate dehydrogenases (IDHs) 1/2 mutations, TP53 mutations, co-deletion of chromosome arms 1p/19q, and BRAF mutation/fusion. "
01/01/2015 - "Recent genetic studies have revealed that the major categories of gliomas, such as circumscribe astrocytomas, infiltrating astrocytomas/oligodendrogliomas, and glioblastoma, roughly correspond to major genetic alterations, including isocitrate dehydrogenases (IDHs) 1/2 mutations, TP53 mutations, co-deletion of chromosome arms 1p/19q, and BRAF mutation/fusion. "

Related Drugs and Biologics

1. ivosidenib
2. venetoclax
3. Iron
4. Azacitidine (5 Azacytidine)
5. Oxidoreductases (Dehydrogenase)
6. Enzymes
7. Methyltransferases
8. ErbB Receptors (EGF Receptor)
9. alpha-hydroxyglutarate
10. DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Chemoradiotherapy
4. Transplantation
5. Fluid Therapy (Oral Rehydration Therapy)