Ribomunyl

a ribosome-component immune modulator (RCIM) consisting of ribosomal & membrane fractions of Klebsiella pneumoniae & ribosomal fractions of Strep pneumoniae & pyogenes & Haemophilus influenzae; for bacterial immunotherapy

Also Known As:

Networked: 28 relevant articles (6 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bousquet, Jean: 2 articles (01/2006 - 01/2006)
2.	Karpova, E P: 1 article (01/2015)
3.	Tulupov, D A: 1 article (01/2015)
4.	Zaplatnikov, A L: 1 article (01/2015)
5.	Barchet, Winfried: 1 article (01/2011)
6.	Bootz, Friedrich: 1 article (01/2011)
7.	Busch, Nicolas: 1 article (01/2011)
8.	Coch, Christoph: 1 article (01/2011)
9.	Hagmann, Cristina Amparo: 1 article (01/2011)
10.	Hartmann, Evelyn: 1 article (01/2011)

Related Diseases

1.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/2006 - "It is concluded that Ribomunyl((R)) is effective in preventing and reducing upper and lower respiratory tract infections in adults. " 07/01/2006 - "The goal of our study was to observe 30 children with recurrent respiratory tract infection, 17 boy and 13 girl, they were treated with Ribomunyl. " 01/01/2006 - "Role of ribomunyl((r)) in the prevention of recurrent respiratory tract infections in adults : overview of clinical results." 01/01/1992 - "This second double-blind study versus placebo was performed on 17 patients with acute respiratory infections (placebo group: eight subjects; Ribomunyl group: nine subjects). " 01/01/1990 - "A total of 60 children (mean age +/- SD 7.6 +/- 3.5 years, range 2 - 14.2 years) with recurrent respiratory infections were treated with bacterial wall extract plus bacterial ribosomes (Immucytal) or placebo sprayed into the nostrils and oropharynx three times a day for 1 or 2-week periods over 3.5 months. "
2.	Infections 01/01/1990 - "Respiratory symptoms improved from the first month in the Immucytal treated children, but not in the placebo group, with a reduction in the incidence of infections in the upper and lower airways. " 01/01/1997 - "Ribomunyl was effective throughout the study period, starting from the first month of treatment: a mean of 1.0 +/- 1.1 recurrences was recorded in the Ribomunyl group as compared to 1.5 +/- 1.4 recurrences in the placebo group; this indicated one-third fewer infections (P = 0.001). " 12/01/2000 - "To perform a meta-analysis using data from all clinical trials and studies of a ribosomal vaccine (Ribomunyl((R))) in order to estimate its overall effect on the number of infections and antibacterial courses used per person. " 05/01/1989 - "The ex vivo study of the chemiluminescence index of polynuclear neutrophils before and after treatment of 6 children who were receiving injectable Ribomunyl for ORL infections showed an increase of more than 600% of the mean value of the index after treatment. " 01/01/2002 - "However, only Ribomunyl (Pierre Fabre Medicament) (containing membrane and ribosomal fractions from four bacterial strains) allowed the authors to obtain a significant enhancement of allostimulatory abilities and cytokine production by Dphi in the absence of active cellular infection. "
3.	Rhinitis 01/01/1997 - "This trial involved 327 patients (168 Ribomunyl treated and 159 placebo cases) with an average of 4.3 +/- 1.8 rhinitis episodes per patient recorded during the year preceding the study. " 01/01/1997 - "Effectiveness of ribosomal fractions of Klebsiella pneumoniae, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and the membrane fraction of Kp (Ribomunyl) in the prevention of clinical recurrences of infectious rhinitis. " 01/01/1997 - "A multicenter, double-blind, placebo-controlled study was conducted to investigate the efficacy of an immunostimulant, Ribomunyl, in the prevention of recurrences of infectious rhinitis in adults. "
4.	Virus Diseases (Viral Diseases) 01/01/2006 - "Thus, Ribomunyl stimulates both the innate and acquired immune systems and offers preventive efficacy against both bacterial and viral infections. "
5.	Chronic Disease (Chronic Diseases) 01/01/2015 - "It is shown that the application of the ribosomal vaccine ribomunyl causes a significant reduction in the occurrence of acute respiratory infections in the frequently ill children, lowers the frequency of exacerbation of chronic diseases of the upper respiratory tract, and allows to decrease the use of antibiotics. "

Related Drugs and Biologics

1.	Immunologic Adjuvants (Immunologic Adjuvant)
2.	Vaccines
3.	Anti-Bacterial Agents (Antibiotics)
4.	Cyclosporine (Ciclosporin)
5.	Methotrexate (Mexate)
6.	Cytokines
7.	Interleukin-6 (Interleukin 6)
8.	Tablets
9.	Immunologic Factors (Immunomodulators)
10.	Interleukin-1beta (Interleukin 1 beta)

Related Therapies and Procedures

1.	Immunotherapy
2.	Injections
3.	Aftercare (After-Treatment)
4.	Therapeutics
5.	Intradermal Injections