|1.||Yanardag, Refiye: 5 articles (05/2014 - 11/2005)|
|2.||Tunali, Sevim: 5 articles (05/2014 - 11/2005)|
|3.||Sakurai, Hiromu: 3 articles (10/2005 - 01/2002)|
|4.||Akev, Nuriye: 2 articles (05/2014 - 10/2011)|
|5.||Can, Ayse: 2 articles (05/2014 - 10/2011)|
|6.||Kordowiak, Anna M: 2 articles (01/2008 - 01/2007)|
|7.||Klein, Andrzej: 2 articles (01/2008 - 01/2007)|
|8.||Yasui, Hiroyuki: 2 articles (10/2005 - 05/2005)|
|9.||Willsky, G R: 2 articles (05/2001 - 03/2000)|
|10.||Goldfine, A B: 2 articles (05/2001 - 03/2000)|
|1.||Body Weight (Weight, Body)
05/01/2014 - "Vanadyl sulfate (100 mg/kg body weight) was given daily by gavage for 60 days. "
01/01/2005 - "Vanadyl sulfate significantly reduced the body weight of non-diabetic and STZ-diabetic rats. "
10/01/2011 - "Vanadyl sulfate administration improved the loss in body weight due to STZ-induced diabetes and decreased the rise in blood glucose levels. "
06/01/2006 - "In the diabetic group given vanadyl sulfate, blood glucose, serum sialic and uric acid levels, serum CAT and LDH activities and brain LPO and NEG levels decreased, but brain GSH and body weight increased. "
10/14/2005 - "When the hyperglycemia of STZ rats was improved by daily intraperitoneal injections of VOSO4 for 10 days at the doses of 7 mg/kg body weight for 5 days, 5 mg/kg for the following 3 days, and then 2.5 mg/kg for 2 days, the P450 and CYP2E1 levels and CYP2E1 activity were lowered than those in the untreated STZ rats. "
|2.||Type 2 Diabetes Mellitus (MODY)
03/01/2000 - "Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies."
09/01/1996 - "Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus."
05/01/1996 - "We compared the effects of oral vanadyl sulfate (100 mg/day) in moderately obese NIDDM and nondiabetic subjects. "
06/01/1995 - "We examined the in vivo metabolic effects of vanadyl sulfate (VS) in non-insulin-dependent diabetes mellitus (NIDDM). "
05/01/1996 - "In contrast, in NIDDM subjects, vanadyl sulfate increased GIR approximately 82% (17.3 +/- 4.7 to 30.9 +/- 2.7 micromol / kg FFM / min, P < 0.05); this improvement in insulin sensitivity was due to both augmented stimulation of Rd (26.0 +/-4.0 vs. 33.6 +/- 2.22 micromol / kg FFM / min, P < 0.05) and enhanced suppression of HGO (7.7 +/- 3.1 vs. 1.3 +/- 0.9 micromol / kg FFM / min, P < 0.05). "
01/01/2001 - "Pretreatment with vanadyl sulfate, followed by transfer to a HE diet, significantly delayed the onset of hyperglycemia. "
01/01/1995 - "However, vanadyl sulfate treated rats reverted to hyperglycemia within 12 to 24 h, depending on the route of administration. "
03/01/1998 - "VOSO4 treatment (total dose = 1.3 mmol/kg) of rats made diabetic 8 days earlier by a single i.v. injection of STZ (60 mg/kg BW) was able to induce a long-term (4 weeks) correction of hyperglycemia while weight gain was re-established. "
01/01/2001 - "However, vanadyl sulfate was ineffective when administered to animals which lost their insulin secretion capacity on protracted HE diet, but substantially reduced the hyperglycemia when given together with exogenous insulin. "
03/01/1995 - "We have recently reported that treatment with vanadyl sulfate 0.75 mg/mL in drinking water eliminates hyperglycemia in a subset of streptozotocin (STZ)-diabetic rats, with some rats remaining unresponsive to such treatment. "
12/01/2001 - "To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl sulfate (VOSO(4)), using glucocorticoid treatment to increase insulin resistance, in aging rats. "
08/01/2000 - "Insulin resistance of the K(+) current was not reversed by vanadyl sulfate. "
12/01/2001 - "Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment."
03/01/2001 - "Vanadyl sulfate (VOSO(4)) is an oxidative form of vanadium that in vitro and in animal models of diabetes has been shown to reduce hyperglycemia and insulin resistance. "
08/01/2004 - "Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats."
03/01/2006 - "These results reveal that diabetes mellitus increased oxidative damage in stomach and spleen tissues and vanadyl sulfate has an ameliorating effect on the oxidative stress via its antioxidant property. "
09/01/1989 - "Oral vanadyl sulfate in treatment of diabetes mellitus in rats."
03/01/2006 - "The administration of vanadyl sulfate may be able to reduce hyperglycemia and hyperlipidemia related to the risk of diabetes mellitus."
05/12/1998 - "Salts of the trace element vanadium, such as sodium orthovanadate and vanadyl sulfate (VS), exhibit a myriad of insulin-like effects, including stimulation of glycogen synthesis and improvement of glucose homeostasis in type I and type II animal models of diabetes mellitus. "
|3.||Blood Glucose (Blood Sugar)
|5.||Cytochrome P-450 CYP2E1 (CYP2E1)