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eptazocine
structure given in first source
Also Known As:
1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazocine; 1,6-Methano-1H-4-benzazonin-10-ol, 2,3,4,5,6,7-hexahydro-1,4-dimethyl-, (1S)-
Networked:
8
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azocines
Cyclazocine: 37
eptazocine: 8
Bridged-Ring Heterocyclic Compounds
Cyclazocine: 37
eptazocine: 8
Related Diseases
1.
Respiratory Insufficiency (Respiratory Failure)
06/01/1997 - "
From these, epidural eptazocine is expected to exert strong spinal analgesia by ϰ-stimulation without μ-action, which produces circulatory and respiratory depression.
"
06/01/1997 - "
A significant analgesic effect (P<0.01) of epidural eptazocine without circulatory and respiratory depression was observed.
"
03/01/1988 - "
These results suggest that eptazocine has different cardiohemodynamic effects than other analgesics and produces mild respiratory depression.
"
12/01/1995 - "
Therefore, epidural eptazocine may make it possible to use lower doses of anesthesia in TIVA, thus reducing the adverse effects associated with TIVA such as hypertension during surgery, intraoperative awareness, postanesthetic respiratory depression, delayed recovery from anesthesia, and neurological signs after anesthesia.
"
2.
Intraoperative Awareness
12/01/1995 - "
Therefore, epidural eptazocine may make it possible to use lower doses of anesthesia in TIVA, thus reducing the adverse effects associated with TIVA such as hypertension during surgery, intraoperative awareness, postanesthetic respiratory depression, delayed recovery from anesthesia, and neurological signs after anesthesia.
"
3.
Delayed Emergence from Anesthesia
12/01/1995 - "
Therefore, epidural eptazocine may make it possible to use lower doses of anesthesia in TIVA, thus reducing the adverse effects associated with TIVA such as hypertension during surgery, intraoperative awareness, postanesthetic respiratory depression, delayed recovery from anesthesia, and neurological signs after anesthesia.
"
4.
Decapitation
02/01/1991 - "
1) Decapitation or concussive head injury (20 g, 30 cm)-induced ischemia in mice: Eptazocine (3,10 mg/kg) prolonged the gasping duration or the survival time in a dose-dependent manner.
"
5.
Unconsciousness (Loss of Consciousness)
10/01/1990 - "
KCN (2 mg/kg, i.v.) induced a temporary loss of consciousness being moderated by eptazocine (1-10 mg/kg) in a dose-dependent manner.
"
Related Drugs and Biologics
1.
Analgesics (Analgesic Drugs)
2.
Pentazocine (Talwin)
3.
Morphine (MS Contin)
4.
Methamphetamine (Desoxyn)
5.
Dihydrotachysterol (AT 10)
6.
Dextromethorphan (Racemethorphan)
7.
Codeine (Codeine Phosphate)
8.
Antitussive Agents (Antitussives)
9.
Opioid Analgesics (Opioids)
10.
fominoben
Related Therapies and Procedures
1.
Anesthesia
2.
Analgesia