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11-bromovincamine (brovincamine)
RN given refers to (3alpha,14beta,16alpha)-isomer
Also Known As:
brovincamine
; 11-bromovincamine fumarate (1:1); bromovincamine fumarate
Networked:
7
relevant articles (
0
outcomes,
3
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vincamine: 99
11-bromovincamine: 7
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vincamine: 99
11-bromovincamine: 7
Indolizines: 3
Indolizidines: 2
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vincamine: 99
11-bromovincamine: 7
Related Diseases
1.
Brain Ischemia (Cerebral Ischemia)
01/01/1992 - "
We evaluated the effect of brovincamine on the circulatory and metabolic state in the brain ischemia with internal carotid artery occlusion accompanying the 'misery perfusion syndrome'.
"
01/01/1989 - "
This method is validated in the assessment of brovincamine effects on regional cerebral perfusion in an experimental model of chronic brain ischemia in the rat.
"
12/01/1987 - "
[Effect of brovincamine fumarate on cerebral ischemia acutely induced by BLCL in SHRSR].
"
12/01/1987 - "
The present study was designed to clarify the effect of brovincamine fumarate (BV 26-723: BV) on the degree of cerebral ischemia acutely induced by bilateral common carotid artery ligation (BLCL) in stroke-resistant spontaneously hypertensive rats (SHRSR).
"
2.
Low Tension Glaucoma
04/01/1999 - "
Effects of oral brovincamine on visual field damage in patients with normal-tension glaucoma with low-normal intraocular pressure.
"
02/01/1996 - "
Prevention of visual field defect progression with brovincamine in eyes with normal-tension glaucoma.
"
04/01/1999 - "
To prospectively study the effect of oral brovincamine, a relatively selective cerebral vasodilator, on further deterioration of visual field in patients with normal-tension glaucoma (NTG) with low-normal intraocular pressure (IOP).
"
02/01/1996 - "
A prospective investigation of the effect of brovincamine fumarate, a Ca2+-channel blocker, on visual field changes in normal-tension glaucoma (NTG).
"
3.
Cerebrovascular Disorders (Cerebrovascular Occlusion)
03/09/1987 - "
A number of clinical studies in patients with cerebrovascular insufficiency or symptoms resulting from multiple cerebral infarctions have shown that brovincamine significantly reduces the number of ischaemic regions and the left/right asymmetry of blood flow to the hemispheres, and brings about general improvement of the microcirculation.
"
07/01/1994 - "
The results suggest that the cerebral vasodilator effect of brovincamine is mainly attributable to the inhibition of Ca2+ influx through the voltage-dependent Ca2+ channels, supporting the reported clinical benefits of this drug in the treatment of cerebrovascular disorders.
"
4.
Stroke (Strokes)
12/01/1987 - "
The present study was designed to clarify the effect of brovincamine fumarate (BV 26-723: BV) on the degree of cerebral ischemia acutely induced by bilateral common carotid artery ligation (BLCL) in stroke-resistant spontaneously hypertensive rats (SHRSR).
"
5.
Cerebral Infarction
03/09/1987 - "
A number of clinical studies in patients with cerebrovascular insufficiency or symptoms resulting from multiple cerebral infarctions have shown that brovincamine significantly reduces the number of ischaemic regions and the left/right asymmetry of blood flow to the hemispheres, and brings about general improvement of the microcirculation.
"
Related Drugs and Biologics
1.
Vasodilator Agents (Vasodilators)
2.
Fumarates
Related Therapies and Procedures
1.
Ligation