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beta-galactoside alpha-2,3-sialyltransferase

transfers sialic acid residue from CMP-N-acetylneuraminic acid to an acceptor galactoside
Also Known As:
CMP N-acetylneuraminate-beta-galactoside alpha-2,3-sialyltransferase; CMP-ANGS-transferase; CMP-Neu5Ac-GAl beta1-3GalNAc alpha-2,3-sialyltransferase; CMP-Neu5Ac-Gal1-3GalNAc alpha-2,3-sialyltransferase; CMP-NeuAc-galactoside (alpha 2-3)-sialyltransferase; CMP-acetylneuraminate-galactoside (alpha 2-3)-sialyltransferase; CMPsialic acid beta-galactosyl-1-3-N-acetylgalactosaminide alpha 2-3-sialyltransferase; Gal beta1,3GalNAc alpha2,3-sialyltransferase; SIAT4A protein, human; SIATFL protein, human; ST3Gal I; ST3Gal II; ST3Gal III; ST3Gal IV; ST3Gal VI; alpha 2-3-sialyltransferase; alpha-2,3-ST(O); asialofetuin sialyltransferase; beta-D-galactoside 3-alpha-sialyltransferase; v-ST3GAL I
Networked: 45 relevant articles (0 outcomes, 7 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Pérez-Garay, Marta: 4 articles (01/2014 - 01/2010)
2. Peracaula, Rosa: 4 articles (01/2014 - 01/2010)
3. Bassagañas, Sònia: 2 articles (01/2014 - 01/2014)
4. Figueras, Joan: 2 articles (01/2014 - 08/2013)
5. de Llorens, Rafael: 2 articles (08/2013 - 01/2010)
6. Pagès, Lluís: 2 articles (08/2013 - 01/2010)
7. Vidal-Vanaclocha, Fernando: 2 articles (08/2013 - 01/2010)
8. Arteta, Beatriz: 2 articles (08/2013 - 01/2010)
9. Kaneda, Yasufumi: 2 articles (01/2012 - 10/2011)
10. Nonomura, Norio: 2 articles (01/2012 - 10/2011)

Related Diseases

1. Adenocarcinoma
2. Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/01/2009 - "Increased mRNA expression of STs (ST6Gal I, ST3Gal III) has been detected in invasive cervical squamous cell carcinoma. "
01/01/2013 - "In summary, our results showed that the high expression of ST3Gal I and ST6Gal I, in skin tumors, is associated with tumors with greater potential for invasion and metastasis, as in the case of squamous cell carcinoma, and this may be related to their behavior."
01/01/2013 - "The expression of ST3Gal I was observed in actinic keratosis (53%), keratoacanthoma (78%), squamous cell carcinoma (73%) and basal cell carcinoma (32%) with statistic differences between basal cell carcinoma and keratoacanthoma (P=0.0239) and basal cell carcinoma and squamous cell carcinoma (P=0.0096); for ST6Gal I, cytoplasmic expression was noted in actinic keratosis (40%), heterogeneous and cytoplasmic expression was noted in keratoacanthoma (67%), squamous cell carcinoma (41%) and basal cell carcinoma (7%) with statistic differences between basal cell carcinoma and squamous cell carcinoma (P=0.0061) and basal cell carcinoma and keratoacanthoma (P=0.0008). "
10/01/2001 - "ST6Gal I expression was enhanced in squamous cell carcinoma of the cervix (P = 0.026, Mann-Whitney U test), but mRNA expression from the other three STs (ST3Gal I, ST3Gal III, and ST3Gal IV) was significantly down-expressed in squamous cell carcinoma of the cervix compared to the normal cervix (P = 0.003, P < 0.001, and P = 0.001, respectively). "
01/01/2013 - "In this study, it was evaluated the expression of ST3Gal I and ST6Gal I in cutaneous epithelial lesions that include actinic keratosis (n=15), keratoacanthoma (n=9), squamous cell carcinoma (n=22) and basal cell carcinoma (n=28) in order to evaluate if sialyltransferases expression is different in premalignant and in malignant tumors. "
3. Neoplasms (Cancer)
4. Carcinoma (Carcinomatosis)
5. Actinic Keratosis

Related Drugs and Biologics

1. beta-galactoside alpha-2,3-sialyltransferase
2. beta-D-galactoside alpha 2-6-sialyltransferase
3. Sialyltransferases
4. 5- acetylneuraminyl- (2- 3)- galactosyl- (1- 4)- (fucopyranosyl- (1- 3))- N- acetylglucosamine (sialyl Lewis x)
5. Messenger RNA (mRNA)
6. N-Acetylneuraminic Acid (Sialic Acid)
7. RNA (Ribonucleic Acid)
8. harpin (messenger)
9. Oligosaccharides
10. Antigens

Related Therapies and Procedures

1. Castration