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8-aminoguanine

Also Known As:

6H-Purin-6-one, 2,8-diamino-1,7-dihydro-

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        8-aminoguanine: 3

Experts

1.	Gillespie, Delbert G: 1 article (12/2016)
2.	Jackson, Edwin K: 1 article (12/2016)
3.	Mi, Zaichuan: 1 article (12/2016)

Related Diseases

1.	Hypertension (High Blood Pressure) 12/01/2016 - "Long-term radiotelemetry studies demonstrated that oral 8-aminoguanosine and 8-aminoguanine (5 mg/kg/day) suppressed deoxycorticosterone/salt-induced hypertension. " 11/01/2023 - "Chronic treatment with 8-aminoguanine attenuates hypertension in deoxycorticosterone/salt rats, prevents strokes, and increases lifespan in Dahl salt-sensitive rats on a high salt diet and attenuates the metabolic syndrome in rats; 8-aminoguanosine retards progression of pulmonary hypertension in rats and anemia and organ damage in sickle cell mice. "
2.	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/01/2023 - "Chronic treatment with 8-aminoguanine attenuates hypertension in deoxycorticosterone/salt rats, prevents strokes, and increases lifespan in Dahl salt-sensitive rats on a high salt diet and attenuates the metabolic syndrome in rats; 8-aminoguanosine retards progression of pulmonary hypertension in rats and anemia and organ damage in sickle cell mice. "
3.	Stroke (Strokes) 11/01/2023 - "Chronic treatment with 8-aminoguanine attenuates hypertension in deoxycorticosterone/salt rats, prevents strokes, and increases lifespan in Dahl salt-sensitive rats on a high salt diet and attenuates the metabolic syndrome in rats; 8-aminoguanosine retards progression of pulmonary hypertension in rats and anemia and organ damage in sickle cell mice. "
4.	Retinal Degeneration 11/01/2023 - "8-Aminoguanine reverses age-associated lower urinary tract dysfunction and retinal degeneration. "
5.	Pulmonary Hypertension 11/01/2023 - "Chronic treatment with 8-aminoguanine attenuates hypertension in deoxycorticosterone/salt rats, prevents strokes, and increases lifespan in Dahl salt-sensitive rats on a high salt diet and attenuates the metabolic syndrome in rats; 8-aminoguanosine retards progression of pulmonary hypertension in rats and anemia and organ damage in sickle cell mice. "

Related Drugs and Biologics

1.	Salts
2.	Desoxycorticosterone (Deoxycorticosterone)
3.	8-aminoguanosine
4.	Inosine
5.	Guanosine