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1,3-dichloro-2-propanol

RN given refers to cpd with specified locants

Also Known As:

1,3-dichloroisopropyl alcohol; 1,3-dichloropropan-2-ol; glycerol 1,3-dichlorohydrin

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - Propylene Glycols: 2
      - alpha-Chlorohydrin: 77
        1,3-dichloro-2-propanol: 8
  - Chlorohydrins: 4
    - alpha-Chlorohydrin: 77
      - 1,3-dichloro-2-propanol: 8

Experts

1.	Guan, Shuang: 2 articles (05/2015 - 02/2014)
2.	Huang, Guoren: 2 articles (05/2015 - 02/2014)
3.	Lu, Jing: 2 articles (05/2015 - 02/2014)
4.	Ishii, Yuji: 1 article (01/2021)
5.	Matsushita, Kohei: 1 article (01/2021)
6.	Morikawa, Tomomi: 1 article (01/2021)
7.	Ogawa, Kumiko: 1 article (01/2021)
8.	Takasu, Shinji: 1 article (01/2021)
9.	Toyoda, Takeshi: 1 article (01/2021)
10.	Yamada, Takanori: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2021 - "In vivo mutagenicity and tumor-promoting activity of 1,3-dichloro-2-propanol in the liver and kidneys of gpt delta rats." 09/01/1990 - "These compounds are genotoxic and 1,3-dichloro-2-propanol induced tumors in rats. " 06/01/2010 - "3-MCPD is from the same family as 1,3-dichloro-2-propanol (1,3-DCP), which is known to cause cancer in animals. "
2.	Non-alcoholic Fatty Liver Disease 05/01/2015 - "Nonalcoholic fatty liver disease induced by 13-week oral administration of 1,3-dichloro-2-propanol in C57BL/6J mice."
3.	Melanoma (Melanoma, Malignant) 01/01/2010 - "1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells."
4.	Inflammation (Inflammations) 03/01/2018 - "1,3-Dichloro-2-propanol evokes inflammation and apoptosis in BV-2 microglia via MAPKs and NF-κB signaling pathways mediated by reactive oxygen species."
5.	Hyperlipidemias (Hyperlipidemia) 02/01/2014 - "1,3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathway."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Calcium
3.	alpha-Chlorohydrin

Related Therapies and Procedures

1.	Oral Administration