alphadolone (alfadolone)

Subscribe to Selected New Research on alphadolone

19 relevant articles (1 outcomes, 0 trials/studies) found for this Bio-Agent

Description: see also record for acetate; RN given refers to (3alpha,5alpha)-isomer

Also Known As:

alfadolone; alphadolone acetate; alphadolone, (3alpha,5beta)-isomer; alphadolone, (3beta,5alpha)-isomer; 21-acetoxy-3-alpha-hydroxy-5-alpha-pregnane-11,20-dione

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 58

Related Diseases

1.	Critical Illness (Critically Ill) 05/01/1983 - "The safety and efficacy of prolonged infusion of alphaxalone/alphadolone (Alfathesin: Glaxo) was assessed in 20 critically ill patients needing sedation during intermittent positive pressure ventilation in a general intensive care unit" Get all the results and reference details, order at left...
2.	Tachycardia (Tachyarrhythmias) 06/27/1997 - "In rats anaesthetised with alphaxalone/alphadolone, electrical stimulation (10 s trains of 1 ms pulses at 80 Hz, 40-80 microA) in the dorsolateral and lateral periaqueductal grey matter (PAG), the midbrain defence area, evoked a pressor response with tachycardia and vasodilatation in the hindlimb" 01/03/1995 - "In rats anaesthetised with alphaxalone/alphadolone, electrical stimulation in the dorsal part of the periaqueductal grey matter (PAG) produced a pressor response with tachycardia and vasodilatation in the hind limb, a pattern known as the 'cardiovascular defence reaction' owing to its resemblance to fear-induced hemodynamic changes" 07/18/1994 - "In rats anaesthetised with alphaxalone/alphadolone, electrical stimulation in the dorsolateral part of the periaqueductal grey matter (PAG; 10 s trains of 1 ms pulses at 80 Hz, 40-80 microA) evoked a pressor response accompanied by tachycardia" 01/01/1992 - "In rats anaesthetised with alphaxalone/alphadolone, electrical stimulation in the dorsal periaqueductal grey matter (PAG) evoked a pressor response with tachycardia, vasodilatation in the hindlimb and hyperpnoea: a pattern of response known as the defence reaction" Get all the results and reference details, order at left...
3.	Body Weight (Weight, Body) 01/01/1988 - "This report describes 75 cases of reliable 1-2-hour surgical anesthesia of newborn to adult squirrel monkeys, with rapid induction and recovery, using a single intramuscular dose of alphaxolone-alphadolone (doses between 11.5 and 30 mg/kg body weight)." 03/01/1975 - "Total rats tolerated to daily administration of 60 mg/kg of alphadolone acetate or of 20 ml/kg of 20 per cent Cremophor solution, without showing significant changes in body weight curves and food intake" 06/01/1984 - "Seizure duration in unilateral electroconvulsive therapy (ECT) was recorded by means of EEG in an intraindividual comparison of etomidate (dissolved in a soy-bean oil emulsion) 0.3 mg/kg and Althesin (alphaxalone 9 mg and alphadolone 3 mg/ml) 0.6 mg/kg with methohexitone 1 mg/kg body weight" Get all the results and reference details, order at left...
4.	Pain (Aches) 04/01/2001 - "Orally administered alphadolone caused statistically significant reductions in morphine use and simultaneous highly significant reductions in pain scores" 07/01/1982 - "Minor complications included one adverse reaction to alphaxalone-alphadolone acetate (Althesin), one prolonged episode of laryngeal spasm after removal of the bronchoscope, and subsequent muscle pain attributed to suxamethonium in 36 patients" Get all the results and reference details, order at left...
5.	Stupor 01/01/1983 - "Acoustic reflex can be elicited with Ketamin-hydrochlorid and Alphaxalone-alphadolone acetate narcosis" Get all the results and reference details, order at left...
18 Diseases and 19 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	alphaxalone (alfaxalone)
2.	Alfaxalone Alfadolone Mixture
3.	Thiopental (Pentothal)
4.	Succinylcholine (Suxamethonium Chloride)
5.	Soybean Oil
6.	Pentobarbital (Nembutal)
7.	Pentagastrin (Peptavlon)
8.	Oxygen
9.	Nitrous Oxide (Laughing Gas)
10.	Morphine (MS Contin)
15 Drugs and Important Bio-Agents and 18 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Intermittent Positive-Pressure Ventilation
2.	Bronchoscopes
3.	Tracheotomy
4.	Microspheres (Microsphere)
5.	Anesthesia
5 Therapies and Procedures and 4 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>