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maytanprine

from stems of Maytenus confertiflorus

Also Known As:

N(2')-deacetyl-N(2')-(1-oxopropyl)maytansine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - Maytansine: 145
      - maytanprine: 2
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Macrocyclic Lactams: 28
    - Maytansine: 145
      - maytanprine: 2

Experts

1.	Kanemaru, Kaori: 1 article (08/2004)
2.	Masuda, Toshiya: 1 article (08/2004)
3.	Nakao, Hiromi: 1 article (08/2004)
4.	Oyama, Yasuo: 1 article (08/2004)
5.	Senokuchi, Kaori: 1 article (08/2004)
6.	Umebayashi, Chisato: 1 article (08/2004)
7.	Yonemori, Shigetomo: 1 article (08/2004)

Related Diseases

1.	Virus Diseases (Viral Diseases) 07/01/1989 - "Models based on experimentally induced disease, include heavy metals and trace elements (lead intoxication in guinea pigs, rabbits, rats, cats and primates; mercury intoxication in rats; aluminium intoxication in rabbits; swayback in goat kids; calcium and magnesium deficient rabbits and primates and calcium deficient cynomolgus monkeys), toxins (IDPN, vincristine, vinblastine, podophyllotoxin, colchicine, maytansine, maytanprine, L-BMAA, lectins, adriamycin), nutritional factors (ascorbic acid deficient guinea pigs), virus infection (spongiform polioencephalomyelitis, attenuated poliovirus, lactate dehydrogenase-elevating virus), and immunological factors (immunization with motor neurons). "
2.	Swayback 07/01/1989 - "Models based on experimentally induced disease, include heavy metals and trace elements (lead intoxication in guinea pigs, rabbits, rats, cats and primates; mercury intoxication in rats; aluminium intoxication in rabbits; swayback in goat kids; calcium and magnesium deficient rabbits and primates and calcium deficient cynomolgus monkeys), toxins (IDPN, vincristine, vinblastine, podophyllotoxin, colchicine, maytansine, maytanprine, L-BMAA, lectins, adriamycin), nutritional factors (ascorbic acid deficient guinea pigs), virus infection (spongiform polioencephalomyelitis, attenuated poliovirus, lactate dehydrogenase-elevating virus), and immunological factors (immunization with motor neurons). "
3.	Leukemia 08/01/2004 - "The results suggest that maytanprine exerts a potent inhibitory action on the growth of human leukemia K562 cells. " 08/01/2004 - "Cytotoxic activity of maytanprine isolated from Maytenus diversifolia in human leukemia K562 cells." 08/01/2004 - "We examined the cytotoxic effect of maytanprine isolated from the methanol extract of Maytenus diversifolia on human leukemia K562 cells using a flow cytometer and compared its cytotoxicity with that of maytansine, a potent cytotoxic maytansinoid. "

Related Drugs and Biologics

1.	Maytansine (Maitansine)
2.	Lectins
3.	Heavy Metals
4.	Vincristine (Oncovin)
5.	Vinblastine (Vinblastine Sulfate)
6.	Trace Elements (Biometals)
7.	Podophyllotoxin (Condylox)
8.	Mercury
9.	Magnesium
10.	Immunologic Factors (Immunomodulators)