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triphenyltin fluoride
induces hypertriglyceridemia in rabbits
Also Known As:
TPTF; fluorotriphenylstannane; triphenyl tin fluoride
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Organometallic Compounds: 64
Organotin Compounds: 41
triphenyltin fluoride: 5
Related Diseases
1.
Hypertriglyceridemia
12/01/1981 - "
The present experiments were conducted to elucidate the mechanism of TPTF-induced hypertriglyceridemia in rabbits by a combined biochemical and ultrastructural approach.
"
10/01/1981 - "
[Triphenyltin fluoride-induced hypertriglyceridemia in rabbits (author's transl)].
"
12/01/1981 - "
Recent work in our laboratory has shown that oral administration of triphenyltin fluoride (TPTF) evokes hypertriglyceridemia in rabbits.
"
2.
Hyperlipidemias (Hyperlipidemia)
12/01/1981 - "
Furthermore, it is possible to provide a new animal model for diabetes and diabetic lipemia by administration of TPTF to rabbits.
"
12/01/1981 - "
TPTF induces diabetic lipemia by inhibiting insulin secretion from morphologically intact rabbit B-cell.
"
01/01/1982 - "
Recently we found that a single oral administration of triphenyltin fluoride to rabbits induces transient diabetes and diabetic lipemia by inhibiting insulin secretion from morphologically normal pancreatic B-cells...
"
12/01/1981 - "
These findings suggest that TPTF inhibits insulin release from rabbit islets, subsequently inducing diabetic lipemia due to the insulin deficiency.
"
3.
Hyperglycemia
03/01/1982 - "
Fasting blood glucose level was elevated and a significant inhibition of insulin (IRI) release in response to the intravenous glucose infusion was observed in TBTF treated rabbits, but the level of blood glucose and the degree of inhibition of IRI release were low compared with those of triphenyltin fluoride treated rabbits, in which much greater fasting hyperglycemia was observed.
"
4.
Folliculitis (Sycosis)
05/01/1982 - "
An occupational irritant contact folliculitis from TPTF in a marine paint plant worker is described.
"
05/01/1982 - "
Occupational irritant contact folliculitis associated with triphenyl tin fluoride (TPTF) exposure.
"
Related Drugs and Biologics
1.
triphenyltin fluoride
2.
Insulin (Novolin)
3.
Irritants (Vesicants)
4.
Glucose (Dextrose)
5.
Blood Glucose (Blood Sugar)
Related Therapies and Procedures
1.
Oral Administration