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NSC 297170
RN given refers to cpd without isomeric designation; structure in first source
Also Known As:
1,2-diethyl-1,2-bis(3'-hydroxyphenyl)ethane; 3,3'-HES; 3,4-bis(3'-hydroxyphenyl)hexane; NSC 297170, (R*,R*)-(+-)-isomer; NSC 297170, (R*,S*)-isomer; NSC-297170; meso-3,4-bis(3'-hydroxyphenyl)hexane; metahexestrol
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzylidene Compounds: 10
Stilbenes: 657
Dihydrostilbenoids: 5
Hexestrol: 29
NSC 297170: 2
Stilbestrols: 1
Hexestrol: 29
NSC 297170: 2
Benzyl Compounds: 2
Bibenzyls: 16
Dihydrostilbenoids: 5
Hexestrol: 29
NSC 297170: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/1982 - "
It cannot be decided whether the partial antiestrogen, 3,4-bis(3'-hydroxyphenyl)hexane unfolds its antimammary tumor activity by means of its estrogenic or its antiestrogenic potency.
"
05/01/1984 - "
The syntheses of symmetrically 4,4'-, 5,5'-, and 6,6'-disubstituted derivatives of the mammary tumor inhibiting antiestrogen metahexestrol [meso-3,4-bis(3-hydroxyphenyl)hexane] (1) are described [4,4'-substituents: F, (2), Cl (3), Br (4), I (5), CH2N (CH3)2 (6), CH3 (7), CH2OCH3 (8), CH2OC2H5 (9), CH2OH (10), NO2 (11), NH2 (12), N(CH3)2 (13), COCH3 (14), and C2H5 (15); 5,5'-substituents: OH (16) and Cl (17); 6,6'-substituents: OH (18), F (19), Cl (20), and CH3 (21)].
"
01/01/1982 - "
Biochemical properties, such as the activities of eight carbohydrate-metabolism-linked enzymes and four acid hydrolases, and histological characteristics of growing and regressing DMBA-induced mammary tumors of the SD-rat after ovariectomy or treatment of the host with hexesterol, tamoxifen, and 3,4-bis(3'-hydroxyphenyl)hexane were determined.
"
Related Drugs and Biologics
1.
Estrogen Receptor Modulators (Antiestrogen)
2.
Tamoxifen
3.
Hydrolases
4.
Hexanes
5.
Enzymes
6.
Acids
7.
hydroxide ion
Related Therapies and Procedures
1.
Ovariectomy (Oophorectomy)