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1-hydroxypyrene

pyrene metabolite; RN given refers to parent cpd
Also Known As:
1-pyrenol
Networked: 30 relevant articles (0 outcomes, 8 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hecht, Stephen S: 3 articles (08/2015 - 03/2008)
2. Carmella, Steven G: 3 articles (08/2015 - 03/2008)
3. Hatsukami, Dorothy K: 2 articles (08/2015 - 03/2008)
4. Khariwala, Samir S: 2 articles (08/2015 - 08/2013)
5. Yueh, Bevan: 2 articles (08/2015 - 08/2013)
6. Stepanov, Irina: 2 articles (08/2015 - 08/2013)
7. Hamakova, Kvetoslava: 2 articles (03/2010 - 02/2010)
8. Kremlacek, Jan: 2 articles (03/2010 - 02/2010)
9. Fiala, Zdenek: 2 articles (03/2010 - 02/2010)
10. Borska, Lenka: 2 articles (03/2010 - 02/2010)

Related Diseases

1. Chromosome Aberrations (Chromosome Abnormalities)
01/01/2014 - "In a group of patients with psoriasis (19), treated with Goeckerman regimen (GR), we evaluated their level of CN, level of chromosomal aberration in peripheral lymphocytes (CA), level of urinary 1-hydroxypyrene (1-OHP) and their value of Psoriasis Area and Severity Index (PASI). "
03/01/2010 - "We evaluated dermal absorption of PAH as well as the genotoxic and apoptotic effects of GT in 20 patients with psoriasis, by determining numbers of chromosomal abnormalities in peripheral lymphocytes, and levels of 1-hydroxypyrene (1-OHP), p53 protein and soluble FasL (sFasL) in urine and/or blood, before and after GT. "
02/01/2010 - "We evaluated dermal absorption of PAHs as well as the mutagenic and genotoxic effects of GR in 16 children with psoriasis, by determining levels of 1-hydroxypyrene (1-OHP), 1-,2-,3-,4-hydroxyphenanthrene, (1-OHPhe, 2-OHPhe, 3-OHPhe, and 4-OHPhe), urinary mutagenicity (Salmonella mutagenicity assay, Ames test) and numbers of chromosomal aberrations in peripheral lymphocytes (CA), in urine and/or blood, before and after GR. "
04/01/2002 - "The aim of this study was to assess the cytogenetic effects of urban air pollution by analyzing the chromosomal aberration (CA) frequencies in lymphocytes and to estimate the polycyclic aromatic hydrocarbons (PAHs) exposure by measuring urinary 1-hydroxypyrene (1-OHP) levels. "
09/01/2012 - "The markers that fulfilled the inclusion criteria are: 1-hydroxypyrene, DNA adducts, chromosomal aberrations, micronuclei, oxidative damage to nucleobases, and methylation changes. "
2. Head and Neck Neoplasms (Head and Neck Cancer)
3. Atopic Dermatitis (Atopic Eczema)
4. Breast Neoplasms (Breast Cancer)
5. Pityriasis Lichenoides (Pityriasis Lichenoides et Varioliformis Acuta)

Related Drugs and Biologics

1. Biological Markers (Surrogate Marker)
2. Coal Tar (Estar)
3. Aromatic Polycyclic Hydrocarbons (Polycyclic Aromatic Hydrocarbons)
4. Glutathione Transferase (Glutathione S-Transferase)
5. DNA (Deoxyribonucleic Acid)
6. 2-naphthol
7. N'-nitrosonornicotine (nitrosonornicotine)
8. Pyrenes
9. Malondialdehyde (Propanedial)
10. Creatinine