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decamethonium (decamethonium bromide)

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RN given refers to parent cpd

Also Known As:

decamethonium bromide; (DM)Br2; decamethonium dibromide; decamethonium dichloride; decamethonium dihydroxide; decamethonium diiodide; decamethonium dipricrate; decamethonium iodide; decamethylenebis(trimethylammonium)bromide

Networked: 51 relevant articles (1 outcomes, 1 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Organic Chemicals: 45
- Amines: 1233
  - Quaternary Ammonium Compounds: 957
    - Bis-Trimethylammonium Compounds: 27
      - Decamethonium Compounds
        decamethonium: 51
- Onium Compounds
  - Quaternary Ammonium Compounds: 957
    - Bis-Trimethylammonium Compounds: 27
      - Decamethonium Compounds
        decamethonium: 51

Experts

1.	Pitsillides, Andrew A: 1 article (04/2006)
2.	Patel, Ketan: 1 article (04/2004)
3.	Otto, William R: 1 article (04/2004)
4.	McKinnell, Iain W: 1 article (04/2004)
5.	Macharia, Raymond: 1 article (04/2004)
6.	Christ, Bodo: 1 article (04/2004)
7.	Cavrini, Vanni: 1 article (02/2003)
8.	Bertucci, Carlo: 1 article (02/2003)
9.	Bartolini, Manuela: 1 article (02/2003)
10.	Andrisano, Vincenza: 1 article (02/2003)

Related Diseases

1.	Myasthenia Gravis 01/01/1974 - "A re-evaluation of the decamethonium test for myasthenia gravis." 05/01/1967 - "[Desmedt and decamethonium tests in the diagnosis of myasthenia gravis]" 05/01/1952 - "The action of decamethonium iodide (C.10) in myasthenia gravis." 07/31/1965 - "The purpose of this paper is to indicate improvement in mortality and morbidity due to three major advances: (1) use of the decamethonium diagnostic test in a myasthenia gravis clinic; (2) improvements in assessment and management of respiratory insufficiency; and (3) avoidance of anticholinesterase treatment in the immediate and early postoperative recovery period.Fourteen" 10/01/1956 - " VI. Effects of anticholinesterase compounds, d-tubocurarine, and decamethonium in patients with myasthenia gravis." Order ALL the reference details at left...
2.	Respiratory Insufficiency (Respiratory Failure) 07/31/1965 - "The purpose of this paper is to indicate improvement in mortality and morbidity due to three major advances: (1) use of the decamethonium diagnostic test in a myasthenia gravis clinic; (2) improvements in assessment and management of respiratory insufficiency; and (3) avoidance of anticholinesterase treatment in the immediate and early postoperative recovery period.Fourteen" Order ALL the reference details at left...
3.	Neuromuscular Diseases (Neuromuscular Disease) 06/01/1975 - "Decamethonium and succinylcholine were used to study the effects of depolarizing muscle relaxants on serum potassium in 60 patinets, free of neuromuscular disease, during major orthopedic surgery. " Order ALL the reference details at left...
4.	Paralysis (Palsy) 08/01/1991 - "In order to investigate further the effects of paralysis on skeletal development in the chick embryo, paralysis was induced at 6 days of incubation by dropping 0.2% solution of decamethonium bromide onto the chorioallantoic membrane and maintaining paralysis through to 20 days of incubation. " 11/01/1981 - "Paralysis by injection of decamethonium in conjunction with artificial ventilation did not reveal systematic differences in cardiovascular response threshold, form, or magnitude between the paralyzed and non-paralyzed state, indicating that the cardiovascular response patterns were not secondary to changes in respiration. " 04/01/1975 - "Decamethonium iodide at a dose of 1 mg per embryo gave maximum survival and paralysis to 18 days of incubation. " 04/15/1966 - "When these fibers are stimulated electrically in the anesthetized dog with skeletal muscle paralysis (induced by decamethonium), the effects are vasoconstriction in the front footpad, cardiac acceleration and augmentation, and a rise in arterial blood pressure." 02/01/1962 - "When decamethonium was left in contact with the isolated muscle, maximum paralysis developed quickly, but then the muscle recovered despite the continued presence of the drug in the bath. " Order ALL the reference details at left...
5.	Seizures (Seizure) 05/07/1949 - "Effects of decamethonium iodide (CIO) on respiration and on induced convulsions in man." 02/01/1951 - "Effects of decamethonium bromide (C 10) and d-tubocurarine on electro-convulsions." 05/14/1949 - "Comparison of decamethonium iodide with d-tubocurarine in controlling electrically induced convulsions." 07/01/1983 - "Moreover, dogs receiving central injections of penicillin showed seizures abolished by administration of decamethonium bromide (100 micrograms X kg-1, i.v.). " 09/01/1969 - "1. The ganglion blocking agents, chlorisondamine, pentamethonium, mecamylamine, decamethonium and hexamethonium all block nicotine extensor convulsions when administered intraventricularly in mice. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Succinylcholine (Suxamethonium Chloride)
2.	Potassium
3.	Neuromuscular Depolarizing Agents
4.	Tubocurarine (Tubocurarine Chloride)
5.	Acetylcholine (Acetylcholine Chloride)
6.	Nicotine
7.	Gallamine Triethiodide (Gallamine)
8.	Edrophonium (Tensilon)
9.	Curare
10.	Hexamethonium (Hexamethonium Bromide)

Related Therapies and Procedures

1.	Positive-Pressure Respiration (PEEP)
2.	Microelectrodes
3.	Intravenous Injections
4.	Injections

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