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benzoquinoxaline

Also Known As:
5,6-benzoquinoxaline; benzo(f)quinoxaline
Networked: 12 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jensen, Frances E: 2 articles (08/2008 - 03/2005)
2. Norenberg, Michael D: 1 article (01/2013)
3. Bethea, John R: 1 article (01/2013)
4. Jayakumar, Arumugam R: 1 article (01/2013)
5. Bracchi-Ricard, Valerie: 1 article (01/2013)
6. Johnstone, Andrea L: 1 article (01/2013)
7. Pearse, Damien D: 1 article (01/2013)
8. Johnstone, Joshua T: 1 article (01/2013)
9. Gao, Han: 1 article (01/2013)
10. Morton, Paul D: 1 article (01/2013)

Related Diseases

1. Spinal Cord Injuries (Spinal Cord Injury)
2. Hyperalgesia
3. Seizures (Seizure)
03/30/2005 - "Finally, in vivo administration of the CaN inhibitor FK-506 significantly suppressed hypoxic seizures, and posttreatment with NBQX (2,3-dihydroxy-6-nitro-7-sulfonyl-benzo[f]quinoxaline) or FK-506 blocked the hypoxic seizure-induced increase in CaN expression. "
02/01/1992 - "The seizures triggered by MPP+ in adult mice were blocked by coadministration of L-glutamate antagonists active at kainate/AMPA receptors such as gamma-D-glutamylaminomethylsulphonate and 2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo[f]quinoxaline. "
06/01/1993 - "The quisqualate antagonists [2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline and 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine] elevated the threshold for ATPA and less so for kainate seizures, whereas the NMDA antagonist 3-((+-)2-carboxypiperazine-4-yl)-propyl-1-phosphonate elevated the threshold for NMDA seizures. "
08/06/2008 - "Postseizure administration of AMPAR antagonists NBQX (2,3-dihydroxy-6-nitro-7-sulfonyl-benzo[f]quinoxaline), topiramate, or GYKI-53773 [(1)-1-(4-aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine] attenuated the AMPAR potentiation, phosphorylation, and kinase activation and prevented the concurrent increase in in vivo seizure susceptibility. "
12/15/1999 - "Pre-treatment of male, Swiss Webster mice with the alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA)/kainate receptor antagonists 1,2,3,4-tetrahydro-6-nitro-2, 3-dioxo-benzo[f]quinoxaline-7-sulfonamide (NBQX; 10-80 mg/kg, i.p.) or 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2, 3-benzodiazepine hydrochloride (GYKI 52466; 10-20 mg/kg, i.p.) failed to significantly attenuate cocaine-induced convulsions or lethality. "
4. Status Epilepticus (Complex Partial Status Epilepticus)
5. Inflammation

Related Drugs and Biologics

1. NADPH Oxidase (NAD(P)H oxidase)
2. acetovanillone (apocynin)
3. 2,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)
4. N-Methylaspartate (NMDA)
5. Capsaicin (Zostrix)
6. Kainic Acid (Kainate)
7. alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)
8. Kainic Acid Receptors (Kainate Receptor)
9. Benzodiazepines
10. Glutamic Acid (Glutamate)