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L-pipecolate dehydrogenase

Also Known As:

pipecolate oxidase; pipecolic acid oxidase

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxidoreductases Acting on CH-NH Group Donors
      - L-pipecolate dehydrogenase: 4

Experts

1.	Asangani, Irfan A: 1 article (05/2013)
2.	Ateeq, Bushra: 1 article (05/2013)
3.	Athanikar, Jyoti N: 1 article (05/2013)
4.	Chinnaiyan, Arul M: 1 article (05/2013)
5.	Khan, Amjad P: 1 article (05/2013)
6.	Mehra, Rohit: 1 article (05/2013)
7.	Michailidis, George: 1 article (05/2013)
8.	Palapattu, Ganesh: 1 article (05/2013)
9.	Rajendiran, Thekkelnaycke M: 1 article (05/2013)
10.	Siddiqui, Javed: 1 article (05/2013)

Related Diseases

1.	Zellweger Syndrome (Zellweger's Syndrome) 07/15/1988 - "Identification of L-pipecolate oxidase in human liver and its deficiency in the Zellweger syndrome." 05/01/1989 - "These findings provide indirect evidence that the marked hyperpipecolinaemia described in a group of human genetic disorders connected with peroxisomal defects such as Zellweger syndrome might be due to the absence of peroxisomal L-pipecolate oxidase." 07/07/1992 - "We have used this assay procedure to detect L-pipecolate oxidase in skin fibroblasts obtained from a control subject and from patients of hyperpipecolic acidaemia and Zellweger syndrome and found that this enzyme activity is present in the control, but absent or decreased in the patients with the peroxisomal disorders."
2.	Inborn Genetic Diseases (Disease, Hereditary) 05/01/1989 - "These findings provide indirect evidence that the marked hyperpipecolinaemia described in a group of human genetic disorders connected with peroxisomal defects such as Zellweger syndrome might be due to the absence of peroxisomal L-pipecolate oxidase."
3.	Peroxisomal Disorders (Peroxisomal Disorder) 07/07/1992 - "We have used this assay procedure to detect L-pipecolate oxidase in skin fibroblasts obtained from a control subject and from patients of hyperpipecolic acidaemia and Zellweger syndrome and found that this enzyme activity is present in the control, but absent or decreased in the patients with the peroxisomal disorders."
4.	Neoplasms (Cancer) 05/01/2013 - "In addition, the expression of sarcosine biosynthetic enzyme, glycine N-methyltransferase (GNMT), was elevated in PCa tissues, while sarcosine dehydrogenase (SARDH) and pipecolic acid oxidase (PIPOX), which metabolize sarcosine, were reduced in prostate tumors. "

Related Drugs and Biologics

1.	Enzymes
2.	Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)
3.	Sarcosine Dehydrogenase
4.	Sarcosine (Methylglycine)