4-azidobenzylcarazolol (pABC)

07/01/2008 - "Although PABC and BC tumor size, grade and type, and lymphovascular and lymphnode invasion were similar, the BC cases showed better overall--(p=0.0001) and disease-free (p-0.015) survival. "
10/01/2023 - "The aim of this study was to describe tumor clinicopathological characteristics and pregnancy outcomes in PABC patients. "
04/01/2023 - "Several studies have shown that PABCs have different genomic signatures than non-PABC tumors, showing increased expression of immune response mediators. "
08/01/2022 - "This study assessed the genomic background of triple-negative PABC tumors by detection of copy number alterations (CNAs). "
05/19/2021 - "In the present study, 35% of PABC patients tested carried pathogenic mutations in two known cancer predisposition genes (BRCA1 and CHEK2). "

04/01/1985 - "The efficacy of pulmonary artery balloon counterpulsation (PABC) was evaluated in improving right ventricular (RV) output during left heart bypass for global cardiac failure. "

01/01/2022 - "Our study revealed that PAPPA was upregulated in PABC tissues and breast cancer cells. "
04/01/2021 - "This study, based on a large population-based cohort of 744 PABC Dutch patients, underlines the more aggressive histopathologic profile compared to age-matched breast cancer patients ≤ 45 years. "
01/01/2020 - "Large studies have shown similar prognosis for women with PABC compared to other young women with breast cancer, when accounting for differences in age, stage and other tumour characteristics."
01/01/2020 - "In studies comparing outcomes in women with PABC to other young breast cancer patients, it is crucial to adjust for age, since the age distribution of PABC depends both on age at pregnancy and age at breast cancer. "
12/01/2019 - "The objective of this study was to find out the incidence of pregnancy-associated breast cancer (PABC) in a tertiary care referral centre and to compare the epidemiological, diagnostic and prognostic factors as well as maternal and foetal outcomes with the most recent literature worldwide. "

03/15/2009 - "The purpose of the current study was to compare locoregional recurrence (LRR), distant metastases (DM), and overall survival (OS) in young patients with PABC and non-PABC. "
06/01/2013 - "This suggests that the heightened aggressiveness of PABC may involve a predisposition to metastasis through extracellular matrix degradation, plus angiogenesis independence. "
06/01/2009 - "If we determine the mechanisms by which involution promotes metastasis of PABC, the post-partum period can be a window of opportunity for intervention strategies."
08/01/2015 - "Although PABC is usually discovered in an advanced stage, breast cancer metastasis on the placenta is a rare event. "
02/07/2011 - "Our study supports the involvement of miR-21 in breast cancer progression and metastasis formation in PABC implying a role of this miRNA as a marker for poor prognosis in PABC patients."

02/01/2022 - "Subgroups were compared to matched non-PABC patients, to investigate the influence of pregnancy and lactation on clinical course and outcome. "
01/01/2009 - "As pregnancy-associated breast cancer (PABC) has a significantly more aggressive clinical course and mortality rate than other forms of breast malignancies, our current study compared tumor suppressor expression in myoepithelial cells of PABC and non-PABC, to determine whether myoepithelial cells of PABC may have aberrant expression of tumor suppressors. "