2- ((5- chloro- 2- methoxyphenyl)azo)- 1H- imidazole

Subscribe to Selected New Research on 2-((5-chloro-2-methoxyphenyl)azo)-1H-imidazole

5 relevant articles (2 outcomes, 0 trials/studies) found for this Bio-Agent

Description: RN given refers to parent cpd; structure in first source

Also Known As:

2-((5-chloro-2-methoxyphenyl)azo)-1H-imidazole hydrochloride; M 6434; M-6434; M6434

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Azoles: 224

Imidazoles: 94

2-((5-chloro-2-methoxyphenyl)azo)-1H-imidazole: 5

Related Diseases

1.	Hemorrhagic Shock 01/01/1984 - "M6434 improved the survival rate of rabbits in hemorrhagic shock" 03/01/1989 - "Mechanisms involved in the effect of M6434 on experimental hemorrhagic shock: II. Effects on energy metabolism and organ blood flow." 03/01/1989 - "Mechanisms involved in the effect of M6434 on experimental hemorrhagic shock: I. Effects on myocardial contractility and venous return." 03/01/1989 - "Dopamine had no effect at 20 micrograms/kg/min, but it increased venous return in both states at 50 micrograms/kg/min. These results suggest that M6434 may improve the hemodynamic derangement in severe hemorrhagic shock through decreasing venous blood pooling." Get all the results and reference details, order at left...
2.	Orthostatic Hypotension (Postural Hypotension) 11/01/1992 - "These results show that M6434 possesses a potent hypertensive effect with a weaker bradycardiac action and suggest that M6434 may be a potential candidate for an anti-hypotensive agent that can prevent the deterioration of hemodynamics in postural hypotension." 11/01/1992 - "In the postural hypotension of anesthetized dogs, M6434 at the doses more than 10 micrograms/kg, i.v. also produced the preventive effects on mean blood pressure and cerebral tissue blood flow" 11/01/1992 - "We examined the effects of M6434 on mean blood pressure and heart rate in conscious rabbits and dogs and on experimental models of postural hypotension in conscious rabbits and anesthetized dogs" 11/01/1992 - "Effects of M6434, an orally active alpha 1-adrenoceptor agonist, on experimental postural hypotension in rabbits and dogs]" 06/01/1992 - "These results suggest that M6434 possesses a potent antihypotensive activity which is superior to that of midodrine, and M6434 may be useful in the treatment of essential and postural hypotension." Get all the results and reference details, order at left...
3.	Cardiogenic Shock 01/01/1984 - "Survival rates of cardiogenic-shock rats improved, and the content of ATP and creatine phosphate in myocardium of these animals were restored by the treatment with 1 or 3 micrograms/kg/min of M6434" Get all the results and reference details, order at left...
4.	Shock 03/01/1989 - "To elucidate the mechanisms of protective effect of M6434 on experimental shock, the authors examined the effects of this compound on the survival time and hemodynamic changes in severely hemorrhagic-shocked dogs" 01/01/1984 - "These results indicate that M6434 may be evaluated as a possible therapeutic agent for shock." 03/01/1989 - "M6434 (20 micrograms/kg/min) increased the venous return of dogs with cardiopulmonary bypass in both shock and normal state" 03/01/1989 - "We also examined the effects of M6434 on contractile tension of isolated canine ventricular strips and on venous return in dogs with cardiopulmonary bypass in normal and shock state" 01/01/1984 - "Effects of 2-[(5-chloro-2-methoxyphenyl)azo]-1H-imidazole (M6434) on hemorrhagic, cardiogenic, and endotoxin shock in rats and rabbits." Get all the results and reference details, order at left...
5.	Hemorrhage 01/01/1984 - "The effects of 2-[(5-chloro-2-methoxyphenyl)azo]-1H-imidazole (M6434) were investigated in experimental models of lethal shock produced by hemorrhage, injection of endotoxin, or coronary ligation" Get all the results and reference details, order at left...
5 Diseases and 5 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Phosphocreatine (Neoton)
2.	Midodrine (Midon)
3.	Adenosine Triphosphate (ATP)
4.	Dopamine (Intropin)
5.	imidazole
5 Drugs and Important Bio-Agents and 3 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Ligation
2.	Cardiopulmonary Bypass (Heart-Lung Bypass)
2 Therapies and Procedures and 2 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>