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N- (N- (3- carboxyoxirane- 2- carbonyl)leucyl)isoamylamine

inhibits calcium-activated neutral protease; see also record for E-64; RN given refers to (2-S-(2alpha,3beta)(R*)-isomer)
Also Known As:
E 64-c; E 64c; E-64-c; E-64c; E64C; EP-475; N-(N-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine, monosodium salt; N-(N-(3-transcarboxyoxirane-2-carbonyl)-L-leucyl)-3-methylbutylamine; N-(N-(L-3-trans-carboxyoxirane -2-carbonyl)-L-leucyl)isoamylamine; Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Khoshchenko, O M: 1 article (02/2005)
2. Kaledin, V I: 1 article (02/2005)
3. Korolenko, T A: 1 article (02/2005)
4. Nikolin, V P: 1 article (02/2005)
5. Spiridonov, V K: 1 article (02/2005)
6. Zhanaeva, S Ya: 1 article (02/2005)
7. Pollack, Jay R: 1 article (09/2003)
8. Witt, Richard C: 1 article (09/2003)
9. Sugimoto, Jeffrey T: 1 article (09/2003)

Related Diseases

1. Infection
2. Hypertrophy
3. Coronary Occlusion
4. Neoplasms (Cancer)
5. Necrosis

Related Drugs and Biologics

1. Cysteine Proteases (Cysteine Protease)
2. Calpain
3. leupeptin
4. Serine Proteases (Serine Protease)
5. Myelin-Associated Glycoprotein (S-MAG)
6. Urea (Carbamide)
7. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
8. RNA (Ribonucleic Acid)
9. Protease Inhibitors (Protease Inhibitor)
10. Aprotinin (Trasylol)

Related Therapies and Procedures

1. Surgical Flaps
2. Ligation
3. Oral Administration