isopropylmalate isomerase

converts alpha-isopropylmalate to beta-isopropylmalate via dimethylcitraconic acid; wild type from S typhimurium composed of two subunits; specific for leucine biosynthesis

Also Known As:

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bardarov, S: 1 article (05/2000)
2.	Bloom, B R: 1 article (05/2000)
3.	Chan, J: 1 article (05/2000)
4.	Hondalus, M K: 1 article (05/2000)
5.	Jacobs, W R: 1 article (05/2000)
6.	Russell, R: 1 article (05/2000)

Related Diseases

1.	Tuberculosis (Tuberculoses) 05/01/2000 - "tuberculosis was created by allelic exchange, replacing wild-type leuD (Rv2987c), encoding isopropyl malate isomerase, with a mutant copy of the gene in which 359 bp had been deleted, creating a strain requiring exogenous leucine supplementation for growth in vitro. "

Related Drugs and Biologics

1.	Leucine (L-Leucine)