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dipyrithione

Also Known As:

2,2'-dithio-bis-pyridine-1-oxide magnesium sulfate; bis(2-pyridyl-1-oxide)disulfide magnesium sulfate; dipyrithione magnesium sulfate; omadine MDS; omadine disulfide

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - dipyrithione: 5

Experts

1.	Yin, Zhimin: 3 articles (10/2013 - 05/2008)
2.	Fan, Yumei: 2 articles (10/2013 - 05/2008)
3.	Huang, Huang: 2 articles (02/2011 - 05/2008)
4.	Luo, Lan: 2 articles (02/2011 - 05/2008)
5.	Pan, Yu: 2 articles (02/2011 - 05/2008)
6.	Elkington, Bethany G: 1 article (12/2021)
7.	Henkin, Joshua M: 1 article (12/2021)
8.	Kinghorn, A Douglas: 1 article (12/2021)
9.	Ren, Yulin: 1 article (12/2021)
10.	Soejarto, Djaja D: 1 article (12/2021)

Related Diseases

1.	Tinea (Ringworm) 12/01/2018 - "Our studies have demonstrated that dipyrithione had a potent antifungal activity in vitro and in vivo, suggesting that it could be formulated as a potential antifungal lead compound in search for novel therapeutic agents against dermatophytosis." 12/01/2018 - "In this study, we determined that dipyrithione could potently inhibit the growth of Trichophyton rubrum, which is the most common cause of dermatophytosis. " 12/01/2018 - "In vivo antifungal activity of dipyrithione against Trichophyton rubrum on guinea pig dermatophytosis models."
2.	Neoplasms (Cancer) 10/21/2013 - "Dipyrithione induces cell-cycle arrest and apoptosis in four cancer cell lines in vitro and inhibits tumor growth in a mouse model." 12/01/2021 - "Of these, the norlignan, nyasol (1b), the triterpenes, pyracrenic acid [3β-O-trans-caffeoylbetulinic acid (3)] and betulinic acid (3b), and the dimeric thiopyridine, dipyrithione (5), were found to show both cancer cell cytotoxicity and anti-infective activity. "
3.	Acute Lung Injury 02/01/2011 - "Dipyrithione attenuates oleic acid-induced acute lung injury."
4.	Shock 05/28/2008 - "Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice."

Related Drugs and Biologics

1.	Oleic Acid (Oleate)
2.	Triterpenes
3.	Lipopolysaccharides
4.	Acids
5.	Betulinic Acid
6.	nyasol
7.	pyracrenic acid