Platelet Glycoprotein GPIb-IX Complex

Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.

Also Known As:

Glycoprotein Ib; CD42a Antigen; CD42b Antigen; CD42c Antigen; CD42d Antigen; Glycoprotein Ib alpha; Glycoprotein Ib beta; Glycoprotein Ib-IX Complex; Platelet Glycoprotein IX; Antigen, CD42a; Antigen, CD42b; Antigen, CD42c; Antigen, CD42d; Glycoprotein Ib IX Complex; Platelet Glycoprotein GPIb IX Complex; Antigens, CD42a; Antigens, CD42b; Antigens, CD42c; Antigens, CD42d; CD42a Antigens; CD42b Antigens; CD42c Antigens; CD42d Antigens; Platelet Membrane Glycoprotein IX; Platelet Membrane Glycoprotein Ib; Platelet Membrane Glycoprotein V

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Platelet Membrane Glycoproteins: 1214
        Platelet Glycoprotein GPIb-IX Complex: 173
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Platelet Membrane Glycoproteins: 1214
        Platelet Glycoprotein GPIb-IX Complex: 173
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Platelet Membrane Glycoproteins: 1214
        Platelet Glycoprotein GPIb-IX Complex: 173
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Platelet Membrane Glycoproteins: 1214
        Platelet Glycoprotein GPIb-IX Complex: 173

glycoprotein receptor GPIb-IX

Bio-Agent Context: Research Results