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2-bromophenol

Also Known As:

o-bromophenol; ortho-bromophenol

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        2-bromophenol: 3

Related Diseases

1.

03/15/1984 - "ortho-Bromophenol at doses greater than 1.6 mmol/kg caused severe renal necrosis in noninduced rats, with consequent elevations in BUN levels. "
09/01/1985 - "These findings are consistent with the view that the kidney necrosis observed after administration of either bromobenzene (1), o-bromophenol (2), or 2-bromohydroquinone (3) might be due in part to 2-bromohydroquinone GSH conjugates formed in the liver and subsequently transported to the kidney and converted to ultimate nephrotoxic metabolite(s)."
01/01/1989 - "3. Bromobenzene and O-bromophenol were both found to be hepatotoxic in English sole, as indicated by the presence of hepatocellular coagulation necrosis and fatty change in the liver, altered glutathione and ascorbic acid levels in liver tissue, elevated serum aspartate aminotransferase and alkaline phosphatase activity and increased serum glucose and triglyceride levels. "

Related Drugs and Biologics

1.	bromobenzene
2.	Triglycerides (Triacylglycerol)
3.	Glutathione (Reduced Glutathione)
4.	Glucose (Dextrose)
5.	Aspartate Aminotransferases (Aspartate Transaminase)
6.	Ascorbic Acid (Vitamin C)
7.	Alkaline Phosphatase
8.	2-bromohydroquinone