|1.||Heijne, Wilbert H M: 3 articles (08/2005 - 03/2003)|
|2.||van Ommen, Ben: 3 articles (08/2005 - 03/2003)|
|3.||van Nesselrooij, Joop H J: 2 articles (07/2007 - 01/2005)|
|4.||Stierum, Rob H: 2 articles (08/2005 - 03/2003)|
|5.||Groten, John P: 2 articles (08/2005 - 01/2005)|
|6.||van Bladeren, Peter J: 2 articles (01/2005 - 03/2003)|
|7.||Yang, Xiaolan: 1 article (06/2014)|
|8.||Yang, Lei: 1 article (06/2014)|
|9.||Wang, Xuping: 1 article (06/2014)|
|10.||Tian, Yanhua: 1 article (06/2014)|
|1.||Brain Edema (Cerebral Edema)
01/01/1994 - "None of these agents led to significant reduction in brain edema formation as measured with a gravimetric column of kerosene and bromobenzene. "
06/01/1993 - "After the decapitation, the specific gravities of the neocortex, caudatoputamen, hippocampus, cerebellum, and midbrain were measured using a variable-density bromobenzene-kerosene column technique as an index of brain swelling. "
01/01/1983 - "The capacity of this sucrose-containing gradient to reveal brain edema was then evaluated by comparing the density values obtained with those measured in the traditional bromobenzene-kerosene gradient as described by Nelson et al. (1971). "
01/01/1982 - "Experiments with acute triethyltin (TET) intoxication in the mouse and the hamster show that the Percoll technique can be used as an alternative to the bromobenzene-kerosene method in quantitative studies on cytotoxic brain edema."
01/01/1987 - "The tissue content of edema fluid was estimated by measuring the specific gravity of selected brain regions, stained or unstained by the tracer dye, on a bromobenzene-kerosene gradient column. "
12/01/1999 - "A density gradient column (1.0250-1.0650 g/cm(3)) comprised of kerosene and bromobenzene was used to assess the presence of edema in regions involved in seizure initiation and propagation that are normally extensively damaged (i.e., piriform cortex and hippocampus). "
09/15/1991 - "Trolox C, a potent inhibitor of lipid peroxidation, prevented the bromobenzene-induced hepatic edema (i.e., the increase in proton MRI signal intensity) and the bioenergetic deterioration (i.e., the decrease in ATP levels). "
02/01/1979 - "It afforded also some protection against the hepatotoxic actions of carbon tetrachloride, bromobenzene and thioacetamide, but did not influence the antiphlogistic activity of paracetamol (carrageenan paw edema test). "
01/01/1971 - "Radioautographic studies indicate that [(14)C]bromobenzene is covalently bound at the sites of necrosis. "
06/01/2006 - "We present here a definitive metabonomic analysis in order to detect novel biomarker and metabolite information, implicating specific putative protein targets in the toxicological mechanism of bromobenzene-induced centrilobular hepatic necrosis. "
01/01/2005 - "The relation between gene expression and metabolite levels was explored and additional insight in the role of various biological pathways in bromobenzene-induced hepatic necrosis was obtained, including the involvement of apoptosis and changes in glycolysis and amino acid metabolism. "
01/01/2005 - "Metabolite levels in plasma or urine were analyzed in relation to changes in hepatic gene expression in rats that received bromobenzene to induce acute hepatic centrilobular necrosis. "
05/01/2001 - "The data showed that a lot of small local necrosis in liver biopsy was observed and serum GST activity was increased after 2 h of treatment with bromobenzene (150 mg/kg i.p.) in mice. "
|4.||Wounds and Injuries (Trauma)
11/01/1987 - "Conversely, model trauma provided almost complete protection from the hepatotoxic effects of a standard dose (200 mg/kg, ip) of bromobenzene. "
10/01/1993 - "Treatment with N-acetylmethionine (NAM) at an ip dose of 1200 mg/kg at 5 hr after bromobenzene administration significantly protected the liver and kidney against injuries. "
03/01/1964 - "PHOSPHATE BALANCE IN GLUTATHIONE-DEPLETED STATES: TOURNIQUET TRAUMA AND BROMOBENZENE INJECTION."
01/01/1987 - "The measurement of serum ADH activity appears to be useful for the detection of acute and early centrilobular hepatic damage, as deduced from the results obtained from experimental hepatic injuries produced by bromobenzene, hypoxia and acute administration of ethanol. "
10/01/2012 - "The present study investigated the effects of an ERα agonist, selective ER modulators (SERMs) and an ER antagonist on drug-induced and chemical-induced liver injuries caused by acetaminophen, bromobenzene, diclofenac, and thioacetamide (TA). "
09/15/1994 - "In addition, the role of the perivenous zone in LCA-induced cholestasis and LCA biotransformation was examined by using bromobenzene (BZ), a chemical that causes selective necrosis of hepatocytes in this zone. "
07/27/2000 - "The magnitude of cholestasis induced by taurolithocholic acid (TLCA) and its relationship with phase I metabolism were analyzed in rats treated with bromobenzene (BZ), a chemical that causes selective necrosis of perivenous (zone 3) hepatocytes. "
04/30/2010 - "Nine chemicals known to induce hepatotoxic effects such as necrosis (2,6-dinitrotolune, bromobenzene, isoniazid, phenacetin, allyl alcohol and thioacetamide), cholestasis (chlorpromazine hydrochloride and alpha-naphthyl isothiocyanate) and oxidative stress (clofibrate) were selected for this study. "
07/01/2007 - "The toxic compounds are expected to induce necrosis (bromobenzene, paracetamol, carbon tetrachloride, iproniazid, isoniazid, thioacetamide), cholestasis (alpha-naphthylisothiocyanate (ANIT), chlorpromazine, ethinylestradiol, methyltestosterone, ibuprofen), or steatosis (phenobarbital, tetracycline). "
|4.||Carbon Tetrachloride (Tetrachloromethane)
|6.||allyl alcohol (allylic alcohol)
|9.||DNA (Deoxyribonucleic Acid)