|1.||Nizet, Victor: 2 articles (09/2009 - 03/2008)|
|2.||Liu, George Y: 2 articles (09/2009 - 03/2008)|
|3.||Wu, Min: 1 article (11/2014)|
|4.||Deng, Xin: 1 article (11/2014)|
|5.||Liu, Xing: 1 article (11/2014)|
|6.||Zhou, Lu: 1 article (11/2014)|
|7.||Lan, Lefu: 1 article (11/2014)|
|8.||Di, Hongxia: 1 article (11/2014)|
|9.||Yang, Cai-Guang: 1 article (11/2014)|
|10.||Chen, Feifei: 1 article (11/2014)|
02/01/2013 - "Detection of increased rates of α-hemolysin and staphyloxanthin inactivation in GO and MMR mutants suggests that these strains are capable of modifying virulence phenotypes implicated in mediating infection. "
01/01/2012 - "These results suggested that this screening method is useful and effective to find compounds targeting staphyloxanthin production, leading to a new type of chemotherapeutics against MRSA infection."
11/18/2014 - "Moreover, inactivation of CcpE results in increased staphyloxanthin production, improved ability to acquire iron, increased resistance to whole-blood-mediated killing, and enhanced bacterial virulence in a mouse model of systemic infection. "
03/07/2008 - "One, previously tested for cholesterol-lowering activity in humans, blocked staphyloxanthin biosynthesis in vitro (median inhibitory concentration approximately 100 nM), resulting in colorless bacteria with increased susceptibility to killing by human blood and to innate immune clearance in a mouse infection model. "
|2.||Cross Infection (Nosocomial Infection)
|3.||Communicable Diseases (Infectious Diseases)
09/01/2009 - "We review several examples of pigments that promote microbial virulence, including the golden staphyloxanthin of Staphylococcusaureus, the blue-green pyocyanin of Pseudomonas spp., and the dark brown or black melanin pigments of Cryptococcus neoformans and Aspergillus spp. Targeted pigment neutralisation might represent a viable concept to enhance treatment of certain difficult infectious disease conditions."
|2.||Virulence Factors (Pathogenicity Factors)
|3.||Reactive Oxygen Species (Oxygen Radicals)