|1.||Delzell, Elizabeth: 7 articles (11/2015 - 09/2005)|
|2.||Sathiakumar, Nalini: 6 articles (11/2015 - 09/2005)|
|3.||Matthews, Robert: 4 articles (09/2009 - 09/2005)|
|4.||Sielken, Robert L: 3 articles (11/2015 - 03/2007)|
|5.||Valdez-Flores, Ciriaco: 3 articles (11/2015 - 03/2007)|
|6.||Melnick, Ronald L: 3 articles (10/2013 - 01/2005)|
|7.||Maldonado, George: 3 articles (09/2009 - 09/2005)|
|8.||Macaluso, Maurizio: 3 articles (09/2009 - 09/2005)|
|9.||Törnqvist, Margareta: 3 articles (09/2009 - 06/2004)|
|10.||Fred, Charlotta: 3 articles (09/2009 - 06/2004)|
01/01/2003 - "Inhaled 1,3-butadiene is carcinogenic in both mice and rats, inducing tumors at multiple sites at all concentrations tested in all identified studies. "
04/01/1993 - "Furthermore, epidemiology studies have consistently revealed associations between occupational exposure to 1,3-butadiene and excess mortality due to lymphatic and hematopoietic cancers. "
06/01/1990 - "The preliminary results of the second study indicate there was induction of tumors similar to those seen in the first study but occurring in response to lower concentrations of 1,3-butadiene."
06/01/1990 - "The available chronic animal studies, however, show an increase in tumor incidence associated with exposure to high concentrations of 1,3-butadiene. "
06/01/1990 - "The available epidemiologic data provide equivocal evidence that 1,3-butadiene is carcinogenic in humans; some available studies suggest that the lymphopoietic system is a target, but there are inconsistencies among studies in the types of tumors associated with 1,3-butadiene exposure, and there is no evidence of a relationship between length of exposure and cancer risk, as one might expect if there was a true causal relationship between 1,3-butadiene exposure and cancer risk. "
|2.||Neoplasm Metastasis (Metastasis)
|3.||Body Weight (Weight, Body)
01/01/1988 - "In the lower concentration range where first-order metabolism applies, metabolic clearance of inhaled 1,3-butadiene per kg body weight was 7300 ml (gas volume) x hr-1 for mice and 4500 ml x hr-1 for rats. "
06/01/1990 - "Maternal toxicity was observed in mice at the 200- and 1000-ppm 1,3-butadiene exposure levels, whereas 40 ppm and higher concentrations of 1,3-butadiene caused significant exposure-related reductions in the mean body weights of male fetuses. "
|4.||Colonic Neoplasms (Colon Cancer)
06/01/1990 - "Previous studies have revealed marked differences in the incidence of leukemia between rats and mice exposed to 1,3-butadiene that do not appear to be readily explained on the basis of pharmacokinetics or metabolism. "
10/01/2010 - "1,3-Butadiene (BD) is a multisite carcinogen in laboratory rodents following lifetime exposure, with greater potency in the mouse than the rat, and is associated with an increase in leukemia mortality in highly exposed workers. "
04/19/2010 - "1,3-Butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen on the basis of epidemiological evidence for an increased incidence of leukemia in workers occupationally exposed to BD and its carcinogenicity in laboratory rats and mice. "
09/01/2009 - "The effect of uncertainty in exposure estimation on the exposure-response relation between 1,3-butadiene and leukemia."
11/01/2008 - "Among census tracts with the highest 1,3-butadiene levels, we observed RRs of 1.40 (95% CI, 1.07-1.81), 1.68 (95% CI, 0.84-3.35), and 1.32 (95% CI, 0.98-1.77) for all leukemia, AML, and ALL, respectively. "
|5.||Maleic Anhydrides (Maleic Anhydride)
|7.||Methylene Chloride (Dichloromethane)