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mesoporphyrin IX

RN given refers to parent cpd; mesoheme is the iron salt of mesoporphyrin IX
Also Known As:
di-HCl of mesoporphyrin IX; ferric mesoporphyrin; mesoheme; mesoporphyrin
Networked: 16 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Wendland, Michael F: 2 articles (12/2002 - 09/2002)
2. Watzinger, Norbert: 2 articles (12/2002 - 09/2002)
3. Saeed, Maythem: 2 articles (12/2002 - 09/2002)
4. Higgins, Charles B: 2 articles (12/2002 - 09/2002)
5. Lund, Gunnar K: 2 articles (12/2002 - 09/2002)
6. Higgins, C B: 2 articles (12/2001 - 02/2001)
7. Saeed, M: 2 articles (12/2001 - 02/2001)
8. Wendland, M F: 2 articles (12/2001 - 02/2001)
9. Ding, Yanfeng: 1 article (07/2008)
10. Schultz, Harold D: 1 article (07/2008)

Related Diseases

1. Iron-Deficiency Anemia (Anemia, Iron Deficiency)
2. Inflammation
3. Arthritis (Polyarthritis)
4. Necrosis
5. Infarction
12/01/2001 - "Treated animals showed reduced infarction size as compared with the control group from 25.6% +/- 7.9 (SD) to 7.9% +/- 6.8 of LV myocardial area (P < .001), as defined with mesoporphyrin-enhanced MR imaging; while the size of the rim increased from 10.8% +/- 10.0 to 16.1% +/- 14.4 (P < .05). "
10/01/1999 - "The size of the mesoporphyrin-enhanced region (37% +/- 4 [SEM] of left ventricular surface area) closely correlated with the true infarction size as measured by means of histomorphometry (36% +/- 3, r = 0.90). "
09/01/2002 - "Mesoporphyrin- (as a necrosis-specific agent) enhanced MR imaging was used to define necrotic myocardium on day 2 after infarction in all 46 animals. "
12/01/1997 - "Myocardial infarction was induced in 8 dogs by ligation of the left anterior descending coronary artery, 4 of which were reperfused after 3 hr Gd-Mesoporphyrin (0.05 mmol/kg) was injected intravenously 210 min after the onset of ischemia (n = 6) or after 24 hr in 2 dogs with non-reperfused infarctions. "
12/01/2002 - "To determine whether the myocardial injury size on day 2 measured after gadolinium (Gd)-mesoporphyrin and Gd-diethylenetriamine-pentaacetic acid (DTPA) administration can be used for predicting left ventricular (LV) remodeling 8 weeks later, and to monitor the structural and functional changes in the infarct, peri-infarct rim, and remote myocardium in reperfused infarction using contrast-enhanced and functional magnetic resonance imaging (MRI) MATERIALS AND METHODS: Myocardial infarction (MI) was induced in 27 rats by 1 hour of coronary occlusion/reperfusion. "

Related Drugs and Biologics

1. Heme Oxygenase (Decyclizing) (Heme Oxygenase)
2. Collagen Type II (Type II Collagen)
3. Tin
4. Prednisolone (Predate)
5. Iron
6. Bilirubin
7. Gadolinium DTPA (Magnevist)
8. Nitroarginine (NG Nitro L Arginine)
9. Contrast Media
10. salicylhydroxamic acid (SHAM)

Related Therapies and Procedures

1. Balloon Occlusion
2. Ligation
3. Lasers (Laser)
4. Spinal Injections