|1.||Hannig, Gerhard: 2 articles (03/2007 - 08/2005)|
|2.||Westlin, William F: 2 articles (03/2007 - 08/2005)|
|3.||Bernier, Sylvie G: 2 articles (03/2007 - 08/2005)|
|4.||Dhanesha, Nirav A: 1 article (01/2014)|
|5.||Jain, Mukul R: 1 article (01/2014)|
|6.||Joharapurkar, Amit A: 1 article (01/2014)|
|7.||Chikara, Shireen: 1 article (01/2013)|
|8.||Reindl, Katie M: 1 article (01/2013)|
|9.||Menon, Jyotsana: 1 article (01/2013)|
|10.||Yildirim, Tuba: 1 article (01/2013)|
03/01/2007 - "This in vivo activity of PPI-2458 was linked to the inhibition of methionine aminopeptidase type 2. Histopathologic assessment of affected joints showed improvement in processes of inflammation, bone resorption, and cartilage erosion, associated with significant improvement in all clinical indices. "
01/01/2008 - "An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis."
01/01/2008 - "To elucidate the role of methionine aminopeptidase type-2 (MetAP-2) in the clinical pathology of rheumatoid arthritis, arthritis was induced in rats by administration of peptidoglycan-polysaccharide (PG-PS). "
|4.||Cryptorchidism (Undescended Testes)
03/01/1991 - "In order to elucidate the reasons for the increased methionine-aminopeptidase activity in the rat cryptorchid testis, a histochemical study was conducted on the changes in testicular aminopeptidase activities using various substrates after the cryptorchidism experimentally was induced with reference to the regenerated hepatic cells which appeared in the partially hepatectomized liver of rat. "
09/08/2005 - "Inhibitors of human methionine aminopeptidase type 2 (hMetAP2) are of interest as potential treatments for cancer. "
01/01/2014 - "Although originally developed as anti-cancer agents, methionine aminopeptidase (MetAP2) inhibitors induce significant and sustained weight reduction. "
11/15/2003 - "Methionine aminopeptidase (MetAP)-2 has been suggested as a novel target for cancer therapy because the anticancer agent TNP-470 irreversibly inactivates the catalytic activity of this enzyme. "
02/01/2003 - "The variation in the effects of TNP-470 was closely related to the diurnal variations in its inhibitory action on methionine aminopeptidase activity in tumor masses. "
|3.||O-(chloroacetylcarbamoyl)fumagillol (TNP 470)
|6.||Serine Proteases (Serine Protease)
|7.||Small Interfering RNA (siRNA)
|8.||Complementary DNA (cDNA)
|10.||Messenger RNA (mRNA)