|1.||White, Carl W: 13 articles (02/2015 - 03/2009)|
|2.||Das, Salil K: 12 articles (01/2012 - 01/2003)|
|3.||Mukherjee, Shyamali: 11 articles (01/2012 - 01/2003)|
|4.||Smith, Milton: 9 articles (03/2011 - 01/2005)|
|5.||Agarwal, Rajesh: 8 articles (07/2014 - 03/2009)|
|6.||Tewari-Singh, Neera: 8 articles (07/2014 - 03/2009)|
|7.||Stone, William L: 7 articles (03/2011 - 01/2006)|
|8.||Smith, Milton G: 7 articles (01/2011 - 07/2002)|
|9.||Veress, Livia A: 5 articles (02/2015 - 05/2010)|
|10.||Hendry-Hofer, Tara B: 5 articles (02/2015 - 05/2010)|
|1.||Wounds and Injuries (Trauma)
07/01/2009 - "The purpose of this study is to assess the ability to detect and monitor progression of half-mustard [2-chloroethylethylsulfide (CEES)] airway injuries with OCT techniques. "
12/15/2011 - "Together, our results show that CEES causes both direct and oxidative DNA damage, suggesting that to rescue SM-caused skin injuries, pleiotropic agents (or cocktails) are needed that could target multiple pathways of mustard skin toxicities."
07/01/2014 - "Results from this study demonstrate the potential therapeutic efficacy of AEOL 10150 against CEES-mediated cutaneous lesions, supporting AEOL 10150 as a medical countermeasure against SM-induced skin injuries. "
01/01/2008 - "The potential therapeutic use of the antibiotic, polymyxin B, was also evaluated since it binds to LPS and could thereby block the enhancement of CEES toxicity by LPS and also inhibit the secondary infections characteristic of HD/CEES wounds. "
01/01/2007 - "Although R24Q Kunitz-domain 1 lacked trypsin and plasmin inhibitory activity, it promoted wound closure of untreated and 2-chloroethyl ethyl sulfide-treated cells but to a much lesser degree. "
|2.||Airway Obstruction (Choking)
01/01/2012 - "These findings indicate that TF pathway inhibition could be an effective strategy to prevent airway obstruction after SM or CEES inhalation."
02/01/2015 - "Intratracheal heparin 1 hr after CEES inhalation improved survival, oxygenation, airway obstruction, and clinical distress. "
10/01/2013 - "Airway obstruction in the form of fibrin-containing casts was evident in central conducting airways of rats receiving CEES. "
12/01/2010 - "To develop a rat inhalation model for airway obstruction with the SM analog 2-chloroethyl ethyl sulfide (CEES), and to investigate the pathogenesis of bronchial cast formation. "
09/26/2008 - "CEES exposure caused lung injury with evidence of fibrosis. "
05/01/2008 - "The data demonstrate that delivery of antioxidants via liposomes to CEES-injured lungs is, depending on liposomal content, protective against ALI, prevents the appearance of proinflammatory mediators in bronchoalveolar fluids, and suppresses progressive fibrosis. "
05/01/2008 - "When lung fibrosis 3 weeks after CEES was quantitated by using hydroxyproline content, liposomes containing NAC or NAC + glutathione had no effects, but liposomes containing alpha/gamma-tocopherol alone or with NAC significantly suppressed the increase in lung hydroxyproline. "
01/01/2009 - "Thus, our study indicates that CEES-induced lung injury is associated with desensitization of beta(2)-AR."
09/26/2008 - "The present study examines the relationship between CEES induced lung injury and MAPKs signaling pathway. "
01/01/2005 - "The present study indicates that CEES causes lung injury and significantly decreases CPT gene expression and activity. "
05/01/2008 - "Accordingly, the liposomal strategy may be therapeutically useful in CEES-induced lung injury in humans."
01/01/2003 - "Therefore, NAC may be an antidote for CEES-induced lung injury."
|5.||Body Weight (Weight, Body)
03/01/1996 - "GST and GAPDH activities in the skin of male hairless mice exposed subcutaneously to CEES (2 mg/kg body weight) were not altered significantly at 2-hr exposure, but decreased up to 60% of that of controls at 8 hr, when oedema formation was greatest. "
03/01/1996 - "Whereas the induction of GST was highest in the lung after multiple intraperitoneal intoxication with CEESO (8 and 32 mg/kg), the decrease in GAPDH activity after exposure to CEES (8 mg/kg body weight) was most remarkable in the spleen, the most susceptible organ to toxicity of CEES. "
01/01/2009 - "The objective of this study was to investigate whether lung injury induced by intratracheal CEES exposure (2 mg/kg body weight) causes desensitization of beta-ARs. "
01/01/2003 - "Within 1 h of exposure to CEES (6 mg/kg body weight), there was 10-fold increase in the (125)I-BSA leakage into lung tissue, indicating severe lung injury. "
01/06/2006 - "In a guinea pig model, initially selected to study the role of an inflammatory cytokine cascade in mustard gas induced lung injury, we observed significant body weight gain in guinea pigs exposed to an intratracheally injected single dose of 2-chloroethyl ethyl sulfide, a mustard analog. "
|5.||2-chloroethyl ethyl sulfide
|6.||Mustard Gas (Sulfur Mustard)
|7.||Conjugated (USP) Estrogens (Premarin)
|8.||Medroxyprogesterone Acetate (Depo-Provera)
|10.||Chemical Warfare Agents
|1.||Estrogen Replacement Therapy
|2.||Hormone Replacement Therapy (Therapy, Hormone Replacement)