|1.||Hulce, Martin: 1 article (06/2003)|
|2.||Schaffert, Courtney: 1 article (06/2003)|
|3.||Waugh, David J J: 1 article (06/2003)|
|4.||Abel, Peter W: 1 article (06/2003)|
|5.||Smith, D David: 1 article (06/2003)|
|6.||Fang, Guoyong: 1 article (06/2003)|
|7.||Saha, Shankar: 1 article (06/2003)|
|8.||Zeng, Wanyun: 1 article (06/2003)|
|9.||Toth, Geza: 1 article (06/2003)|
12/15/1992 - "Further conformational restriction at position 2 in the sequence, as achieved through substitution of D- or L-tetrahydro-3-isoquinoline carboxylic acid (Tic), produced a configuration-dependent differential effect on receptor selectivity and intrinsic activity, leading to a potent mu-selective mu agonist (the D-Tic2 analog) with increased intrinsic activity in the mouse vas deferens assay and to a potent delta-selective delta antagonist (the L-Tic2 analog). "
10/01/1990 - "Analogs of oxytocin containing tetrahydroisoquinoline carboxylic acid (Tic) of L or D configuration in position 2 were synthesized and their biological activities were tested. "
06/05/2003 - "The C-terminal Phe was replaced by Gly, cyclohexylalanine (Cha), Tyr, all four isomers of beta-methylphenylalanine (beta-MePhe), and l- and d-tetrahydroisoquinoline carboxylic acid (Tic), resulting in analogues 3-11. "
12/27/1995 - "The delta selectivity and antagonism of peptides containing L-tetrahydro-3-isoquinoline carboxylic acid (Tic) in second position can be attributed mainly to the Tyr-Tic unit. "
05/01/1989 - "The compounds, D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Pen-Thr-NH2 (CTP), D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP), D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP), D-tetrahydroisoquinoline carboxylic acid (D-Tic)-Cys-Tyr-D-Trp-Lys-Thr-Pen-Thr-NH2 (D-Tic-CTP), D-Tic-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (D-Tic-CTOP) and D-Tic-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (D-Tic-CTAP), were tested in vitro and in vivo for agonist and antagonist potency and selectivity. "
|3.||Cytidine Triphosphate (CTP)
|4.||2- tyrosyl- 1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acid
|5.||1,2,3,4- tetrahydro- 3- isoquinolinecarbonyl- cysteinyl- tyrosyl- tryptophyl- arginyl- threonyl- penicillamyl- threoninamide
|6.||phenylalanyl- cyclo(cysteinyltyrosyl- tryptophyl- ornithyl- threonyl- penicillamine)threoninamide (CTOP)