perfilcon A

consists of 26% terpolymer of 2-hydroxymethylmethacrylate, vinylpyrrolidone & other methacrylates; used as hydrogel lenticular implant

Also Known As:

Permalens; 2-Propenoic acid, 2-methyl-, polymer with 1-ethenyl-2-pyrrolidinone and 2-hydroxyethyl 2-methyl-2-propenoate

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Vinyl Compounds: 2
        Polyvinyls: 183
        Povidone: 536
        perfilcon A: 11
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acrylates: 212
      - Polymethacrylic Acids
        Methylmethacrylates
        perfilcon A: 11
Macromolecular Substances: 97
- Polymers: 13051
  - Plastics: 13104
    - Polyvinyls: 183
      - Povidone: 536
        perfilcon A: 11
    - Synthetic Resins: 101
      - Acrylic Resins: 282
        Polymethacrylic Acids
        Methylmethacrylates
        perfilcon A: 11
Biomedical and Dental Materials
- Polymers: 13051
  - Plastics: 13104
    - Polyvinyls: 183
      - Povidone: 536
        perfilcon A: 11
    - Synthetic Resins: 101
      - Acrylic Resins: 282
        Polymethacrylic Acids
        Methylmethacrylates
        perfilcon A: 11
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Plastics: 13104
        Polyvinyls: 183
        Povidone: 536
        perfilcon A: 11
        Synthetic Resins: 101
        Acrylic Resins: 282
        Polymethacrylic Acids
        Methylmethacrylates
        perfilcon A: 11
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Povidone: 536
        perfilcon A: 11

Related Diseases

1.	Refractive Errors (Refractive Error) 01/01/1992 - "Previous nonhuman primate experimentation has demonstrated the successful use of Permalens hydrogel intracorneal lens implants for the correction of hyperopic and myopic refractive errors. " 07/01/1997 - "To assess the efficacy, stability, and safety of Permalens hydrogel intracorneal lenses for the correction of spherical ametropia 6 years after implantation. " 07/01/1997 - "Permalens hydrogel intracorneal lenses for spherical ametropia."
2.	Myopia 02/01/1983 - "The long-term effects of extended wear contact lenses (Perfilcon A [Permalens]) for myopia have been studied among 400 patients in a private clinic from December 1977 to September 1982. " 11/01/1981 - "The long-term effects of an extended-wear contact lens (perfilcon A [Permalens]) for myopia were evaluated in 106 patients who had successfully worn the lens for four to eight years (median, 4.94 years). "
3.	Dehydration (Water Stress) 04/01/1982 - "Changes in the Permalens with dehydration-complication and management." 05/15/1985 - "These values were not significant when compared to those for five control patients (13.75% water loss for the Permalens and 7.28% for the Bausch & Lomb contact lens), suggesting that other factors may be more significant in controlling hydrogel contact lens dehydration."
4.	Aphakia 01/01/1982 - "Permalens contact lenses for extended wear offer further possibilities for correcting aphakic eyes. " 01/01/1982 - "[Correction of aphakia with permalens lenses (author's transl)]." 06/01/1981 - "The use of the Cooper Permalens soft contact lens as an extended wear lens for correction of aphakia was investigated in 177 eyes. "
5.	Ulcer 10/01/1982 - "Four previously successfully fitted patients with either American Optical Company's Sofcon or Cooper Laboratories' Permalens for extended wear developed corneal ulcers either directly under the lenses or shortly after removal. "

Related Drugs and Biologics

1.	perfilcon A
2.	Hydrogels

Related Therapies and Procedures

1.	Lenses
2.	Contact Lenses
3.	Extended-Wear Contact Lenses (Contact Lenses, Extended Wear)
4.	Hydrophilic Contact Lenses (Hydrophilic Contact Lens)