|1.||Samadi, Abdelouahid: 4 articles (01/2011 - 07/2010)|
|2.||Marco-Contelles, José: 4 articles (01/2011 - 07/2010)|
|3.||García, Antonio G: 4 articles (01/2011 - 07/2010)|
|4.||Villarroya, Mercedes: 4 articles (01/2011 - 07/2010)|
|5.||López, Manuela G: 4 articles (01/2011 - 07/2010)|
|6.||Romero, Alejandro: 4 articles (01/2011 - 07/2010)|
|7.||Turchin, Konstantin F: 3 articles (02/2014 - 08/2012)|
|8.||Dezhenkova, Lyubov G: 3 articles (02/2014 - 08/2012)|
|9.||Shtil, Alexander A: 3 articles (02/2014 - 08/2012)|
|10.||Bekker, Olga B: 3 articles (02/2014 - 08/2012)|
01/01/2011 - "The neuroprotective profile of molecules 11-22 has been investigated in SH-SY5Y neuroblastoma cells stressed with a mixture of oligomycin-A/rotenone. "
09/01/2010 - "Human neuroblastoma SH-SY5Y cells were subjected to a mitochondrial oxidative stress, by blockade of mitochondrial complexes I and V with rotenone and oligomycin-A (R/O); cells were treated for 24 hr with R/O. "
07/22/2010 - "The compounds presented an interesting neuroprotective profile in SH-SY5Y neuroblastoma cells stressed with rotenone/oligomycin A. "
01/15/2011 - "The in vitro pharmacological analysis showed that the neuroprotective profile of the target molecules was in general low, with values ranging from 0% to 18.7%, in human neuroblastoma cells stressed with a mixture of rotenone/oligomycin-A, being nitrones 18, and 6-8 the most potent, as they show values in the range 24-18.4%."
08/15/2010 - "In the LDH test, only compounds 26, 3, 22, and 24 showed neuroprotection with values in the range 37.8-31.6% in SH-SY5Y neuroblastoma cells stressed with a mixture of oligomycin-A/rotenone, but in the MTT test only compound 17 (32.9%) showed a similar profile. "
08/01/2012 - "The acyclic oligomycin A derivative retained the ability to induce apoptosis in tumor cells at low micromolar concentrations, whereas its antimicrobial potencies decreased substantially. "
01/01/2009 - "A new strain of Streptomyces avermitilis produces high yield of oligomycin A with potent anti-tumor activity on human cancer cell lines in vitro."
02/01/2013 - "Despite the previous report demonstrating that oligomycin suppressed TNF-induced apoptosis, in our screening of small molecules enhancing cancer cell death to TRAIL, oligomycin A (OMA) was found to enhance TRAIL-induced apoptosis in HeLa cells. "
01/01/2011 - "Oligomycin-A (Oli-A), an anticancer drug, was loaded to the folate (FA)-conjugated chitosan as a tumor-targeted drug delivery system for the purpose of overcoming the nonspecific targeting characteristics and the hydrophobicity of the compound. "
03/15/2015 - "Surprisingly, oligomycin-A sensitized leukemia cells to BCR-ABL inhibition at concentrations of 100- to 1,000-fold below those required for inhibition of respiration. "
03/15/2015 - "Importantly, oligomycin-A enhanced elimination of BCR-ABL(+) leukemia cells by TKI in a mouse model and in primary blast crisis CML samples. "
02/01/2014 - "NMR parameters demonstrate the striking similarity of the geometry (conformation) of the fragment C20-C34 in the non-cyclic products of retroaldol degradation and the starting antibiotic 1. The compounds obtained had lower cytototoxic properties than oligomycin A for human leukemia cells K-562 and colon cancer cells HCT-116 and lower activity against growth inhibition of model object Streptomyces fradiae. "
03/15/2015 - "We showed that the mitochondrial ATP-synthase inhibitor oligomycin-A greatly sensitized leukemia cells to TKI in vitro. "
06/01/2013 - "The mesylated oligomycin A and 33-deoxy-33-azidooligomycin A did not inhibit F0F1 ATFase ATPase; however, 33-azido-33-deoxy-oligomycin A and the derivatives containing 4-phenyltriazole, 4-methoxycarbonyl-triazole and 3-dimethylaminoethyl amide of carboxyltriazole substituents demonstrated a high cytotoxicity against K562 leukemia and HCT116 human colon carcinoma cell lines whereas non-malignant skin fibroblasts were less sensitive to these compounds. "
|2.||Adenosine Triphosphatases (ATPase)
|4.||Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)
|8.||Folic Acid (Vitamin M)
|9.||Deoxyglucose (2 Deoxy D glucose)
|10.||Adenosine Triphosphate (ATP)