|1.||Fournet, G: 3 articles (01/2013 - 01/2001)|
|2.||Quash, G: 3 articles (01/2013 - 01/2001)|
|3.||Muzio, G: 3 articles (01/2001 - 12/2000)|
|4.||Chantepie, J: 2 articles (01/2009 - 01/2001)|
|5.||Reichert, U: 2 articles (01/2009 - 01/2001)|
|6.||Canuto, Rosa A: 2 articles (02/2003 - 02/2003)|
|7.||Maggiora, Marina: 2 articles (02/2003 - 02/2003)|
|8.||Trombetta, Antonella: 2 articles (02/2003 - 02/2003)|
|9.||Martinasso, Germana: 2 articles (02/2003 - 02/2003)|
|10.||Muzio, Giuliana: 2 articles (02/2003 - 02/2003)|
08/01/2013 - "Members of the ALDH3 family play critical roles in the development of cancer and Sjögren-Larsson syndrome in humans, but have not been studies in groups other than mammals. "
10/01/1992 - "So we suggested that BCP 54 is an AIDH with kinetic properties different from the rat tumor-associated AIDH."
10/01/1992 - "From the high similarity of BCP 54 with tumor-associated AIDH in structural form, it is suggested that BCP 54 has AIDH activity. "
01/01/2009 - "An intraperitoneal (IP) monotherapy in nu/nu mice with subcutaneous xenografts of a human prostate epithelial cancer cell line:DU145 was undertaken with an aldehyde dehydrogenase 3 inhibitor MATE, that is a potent apoptogen on (DU145) in culture but not on their human prostate epithelial normal counterparts  . "
01/01/2013 - "One member of the α,β-acetylenic N-substituted aminothiol ester family is an "active-enzyme-dependent", competitive, irreversible inhibitor of ALDH1 in vitro, an inhibitor of ALDH1 and ALDH3 in rat and human cancer cells in culture, an irreversible apoptogen on chemoresistant bcl2(+++) murine lymphoid and human epithelial cancer cells but a reversible cytostatic compound on human prostate epithelial normal cells in culture."
08/01/1992 - "The ALDH3 gene produces a cytosolic ALDH3 isozyme existing in the stomach and liver carcinoma but hardly in normal liver. "
01/15/1994 - "In in vitro studies, no turnover of aldophosphamide and mafosfamide was observed with the tumor-specific aldehyde dehydrogenase 3 isozyme (ALDH3) isolated from human stomach mucosa as well as from lung (A549) and pharynx (UMSCC2) carcinoma cell lines. "
01/30/2001 - "Aldehyde dehydrogenase 3 gene regulation: studies on constitutive and hypoxia-modulated expression."
08/28/1998 - "Our data indicate that hypoxia exerts cell type-specific effects on both constitutive and induced ALDH3 expression."
08/28/1998 - "In contrast, hypoxia has no effect on constitutive or aromatic hydrocarbon-inducible ALDH3 expression in HTC cells. "
08/28/1998 - "Likewise, aromatic hydrocarbon-induced ALDH3 expression in H4-II-EC3 cells is significantly reduced by hypoxia. "
08/28/1998 - "Hypoxia sharply down-regulates constitutive ALDH3 expression in corneal epithelial cells. "
|4.||Hepatocellular Carcinoma (Hepatoma)
01/30/2001 - "This phenomenon occurs in rat hepatoma systems in which ALDH3 expression is xenobiotic-inducible as well as in rat primary corneal epithelial cells that exhibit high constitutive ALDH3 expression. "
01/30/2001 - "The results confirm that in hepatoma cells ALDH3 expression is closely related with cell growth, and that its inhibition is important in reducing the proliferation of hepatoma cells overexpressing ALDH3."
01/30/2001 - "Several changes in ALDH isoenzyme expression take place in hepatoma cells, in particular cytosolic class 3 ALDH (ALDH3), not expressed in normal hepatocytes, appears and increases with the degree of deviation. "
01/30/2001 - "The products of lipid peroxidation are good substrates for ALDH, but when their intracellular levels are increased in hepatoma cells treated repeatedly with prooxidants, they inhibit ALDH3 and bring about growth inhibition or cell death. "
01/30/2001 - "It has been observed that hepatoma cells expressing low ALDH3 activity are more susceptible to growth inhibition by low concentration of lipid peroxidation products than hepatoma cells expressing high ALDH3 activity. "
01/01/1989 - "These results indicate the presence of specific anti-BCP 54 autoantibodies in sera from a Behçet's patient and suggest that autoantibodies may play a role in the etiopathogenesis of uveitis."
04/01/1994 - "T cell mediated immune responses against the cornea specific protein BCP 54 have been observed in patients with uveitis, Fuchs' heterochromic cyclitis, and corneal disease. "
|1.||bovine corneal protein 54 (aldehyde dehydrogenase 3)
|5.||aldehyde dehydrogenase 1
|9.||Cytochrome P-450 CYP1A1 (CYP1A1)
|10.||Complementary DNA (cDNA)
|1.||Heterologous Transplantation (Xenotransplantation)