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succinyldisalicylic acid

acylates hemoglobin and sickle hemoglobin

Also Known As:

bis(o-carboxyphenyl)succinate; diaspirin

Networked: 34 relevant articles (4 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Hydroxybenzoates: 18
        Salicylates: 2339
        Aspirin: 29782
        succinyldisalicylic acid: 34

Experts

1.	Chin-Yee, I H: 2 articles (10/2003 - 10/2000)
2.	Martin, C M: 2 articles (10/2003 - 10/2000)
3.	Sibbald, W J: 2 articles (10/2003 - 10/2000)
4.	Bedőcs, Peter: 1 article (01/2020)
5.	Szebeni, János: 1 article (01/2020)
6.	Alvaro, Gabriele: 1 article (10/2019)
7.	Avancini, Daniele: 1 article (10/2019)
8.	Baiardo Redaelli, Martina: 1 article (10/2019)
9.	Belletti, Alessandro: 1 article (10/2019)
10.	Bellomo, Rinaldo: 1 article (10/2019)

Related Diseases

1.	Hemorrhage 09/01/1994 - "The efficacy of diaspirin crosslinked hemoglobin solution resuscitation in a model of uncontrolled hemorrhage." 01/01/1997 - "Diaspirin crosslinked hemoglobin (DCLHb Baxter Healthcare Corp., Round Lake, IL, USA), a hemoglobin-based blood substitute has been found to be an effective resuscitative agent following hemorrhage in animals. " 05/01/1996 - "The purpose of this study was to test whether the "blood substitute" diaspirin crosslinked hemoglobin (DCLHb, Baxter Healthcare, Round Lake, IL) might be more effective than lactated Ringer's solution (LR) at restoring tissue oxygenation, as measured by ScvO2, when used as a resuscitative fluid following hemorrhage. " 09/01/1994 - "Since diaspirin crosslinked hemoglobin (DCLHb) is a vasoactive, oxygen-carrying solution, we compared the effects of DCLHb with other resuscitative fluids on blood loss, hemodynamics, and tissue oxygen delivery in a model of uncontrolled hemorrhage. " 01/01/1995 - "This study compared BT following hemorrhage and resuscitation with lactated Ringer's solution (LR) or diaspirin crosslinked hemoglobin solution (DCLHb). "
2.	Brain Ischemia (Cerebral Ischemia) 01/01/1997 - "Prior studies indicate that alpha-alpha diaspirin crosslinked hemoglobin (DCLHb) decreases cerebral ischemia. " 12/01/1997 - "Hemodilution with diaspirin crosslinked hemoglobin (DCLHb) ameliorates occlusive cerebral ischemia. " 01/01/1994 - "Diaspirin crosslinked hemoglobin (DCLHb): effect of hemodilution during focal cerebral ischemia in rats." 07/01/1998 - "A previous study indicated that diaspirin-crosslinked hemoglobin (DCLHb) decreases cerebral ischemia after subarachnoid hemorrhage. "
3.	Hemorrhagic Shock 01/01/1995 - "Resuscitation with Diaspirin Crosslinked Hemoglobin in a pig model of hemorrhagic shock." 06/01/2000 - "Diaspirin-crosslinked hemoglobin reduces mortality of severe hemorrhagic shock in pigs with critical coronary stenosis." 09/01/1996 - "This study examined the effects of administering 0.5, 4, 10, and 30 mL/kg of Diaspirin Crosslinked Hemoglobin (DCLHb) in a swine model of non-lethal hemorrhagic shock. " 01/01/2006 - "Effects of Diaspirin Crosslinked Hemoglobin (DCLHb) on microcirculation and local tissue pO2 of striated skin muscle following resuscitation from hemorrhagic shock." 01/01/2006 - "The hemoglobin based oxygen carrier (HBOC) Diaspirin Crosslinked Hemoglobin (DCLHb) has been developed to substitute not only the blood volume, but also to restore the oxygen-carrying properties of blood during hemorrhagic shock. "
4.	Shock 03/01/1999 - "Comparison of resuscitation with diaspirin crosslinked hemoglobin (DCLHb) vs fresh blood in a rat burn shock model." 03/01/1999 - "Diaspirin crosslinked hemoglobin (DCLHb; Baxter Healthcare Corp, Deerfield, IL) is hemoglobin-based oxygen carrier which, in our laboratory, improved hemodynamic parameters in a rat burn shock model. "
5.	Burns 03/01/1999 - "Comparison of resuscitation with diaspirin crosslinked hemoglobin (DCLHb) vs fresh blood in a rat burn shock model." 03/01/1999 - "Diaspirin crosslinked hemoglobin (DCLHb; Baxter Healthcare Corp, Deerfield, IL) is hemoglobin-based oxygen carrier which, in our laboratory, improved hemodynamic parameters in a rat burn shock model. "

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)
2.	diaspirin-cross-linked hemoglobin
3.	Solutions
4.	Oxygen (Dioxygen)
5.	Ringer's Lactate
6.	Human Serum Albumin
7.	Colloids (Colloid)
8.	Crystalloid Solutions
9.	Blood Substitutes (Artificial Blood)
10.	Thromboxanes

Related Therapies and Procedures

1.	Resuscitation
2.	Hemodilution
3.	Catheters
4.	Hepatectomy