dansylglutamyl-glycyl-arginine chloromethyl ketone

inactivates bovine factor Xa

Also Known As:

1,5-dansyl-L-glutamylglycyl-L-arginine chloromethyl ketone; 5-dimethylaminonaphthalene-1-sulfonylglutamyl-glycyl-arginine chloromethyl ketone; DGGACMK; EGRck; dansyl-GGACK; dansyl-Glu-Gly-Arg-chloromethyl ketone; Glycinamide, N-((5-(dimethylamino)-1-naphthalenyl)sulfonyl)-L-alpha-glutamyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-, (S)-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Che, Sara P Y: 1 article (01/2017)
2.	Park, Jeannie Y: 1 article (01/2017)
3.	Stokol, Tracy: 1 article (01/2017)

Related Diseases

1.	Vascular System Injuries 11/01/1995 - "Neither heparin plus antithrombin III (AT III) nor dansyl Glu Gly Arg chloromethyl ketone-treated factor Xa (DEGR-Xa), a selective inhibitor of thrombin generation, prevented LPS-induced vascular injury. " 04/15/1995 - "Neither heparin alone, heparin plus antithrombin III, or dansyl-Glu-Gly-Arg-chloromethyl ketone-treated factor Xa, a selective inhibitor of thrombin generation, prevented LPS-induced vascular injury 6 hours after LPS administration, whereas these substances significantly inhibited the increase in serum FDP (E) at that time. "
2.	Neoplasms (Cancer) 01/01/2017 - "These changes were decreased with an anti-TF antibody, FXa inhibitors (FPRCK and EGRCK), and PAR-1 antagonist (E5555), demonstrating that FXa generated by TF-expressing tumor-derived EV was signaling through endothelial PAR-1. "

Related Drugs and Biologics

1.	Factor Xa (Coagulation Factor Xa)
2.	Thrombin
3.	Heparin (Liquaemin)
4.	Antithrombin III
5.	dansyl-glutamyl-glycyl-arginyl chloromethyl ketone-treated factor Xa
6.	phenylalanyl- prolyl- arginine- chloromethyl ketone (PPACK)
7.	formycin diphosphate (FDP)