varicella-zoster immune globulin (VZIG)

for passive immunization of suceptible immunodeficient patients exposed to varicella-zoster virus; if term is used therapeutically, do not use subheading /ther use; enter term without subheading and add IMMUNIZATION, PASSIVE

Also Known As:

Networked: 99 relevant articles (9 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bate, Jessica: 4 articles (07/2022 - 06/2011)
2.	Koren, Gideon: 4 articles (11/2013 - 03/2002)
3.	Heath, Paul T: 3 articles (07/2022 - 09/2011)
4.	Hambleton, Sophie: 3 articles (01/2019 - 06/2011)
5.	Centers for Disease Control and Prevention (CDC): 3 articles (07/2013 - 03/2006)
6.	Amirthalingam, Gayatri: 2 articles (07/2022 - 01/2022)
7.	Andrews, Nick: 2 articles (07/2022 - 01/2022)
8.	Gower, Charlotte: 2 articles (07/2022 - 01/2022)
9.	Duchon, Jennifer M: 2 articles (09/2020 - 01/2019)
10.	Gershon, Anne A: 2 articles (09/2020 - 01/2019)

Related Diseases

1.	Chickenpox 01/11/2021 - "These data indicate that VARIZIG may reduce severity of varicella in immunocompromised children and adults. " 01/11/2021 - "There were no varicella- or VARIZIG-related deaths. " 09/17/2020 - "Varicella incidence and morbidity were low in in utero-exposed infants and zero in preterm infants who received prophylactic VARIZIG. " 09/17/2020 - "There were no deaths attributable to varicella or VARIZIG. " 01/01/2020 - "In cases of perinatal exposure, PEP with VZIG should be administered to neonates if the mother develops clinical chickenpox between seven days before delivery and seven days after delivery; in the previous guidelines this was between five days before delivery and two days after delivery. "
2.	Infections 08/01/1998 - "If exposure occurs, VZIG should be administered within 96 hours in an attempt to prevent maternal infection. " 04/01/1983 - "VZV infection occurred in 49 (60.4%) of 81 recipients of VZIG and in 57 (68.6%) of 83 recipients of ZIG. " 12/01/2016 - "The study concludes that few women developed infection after VZIG and none developed pneumonia. " 12/01/2016 - "The aim of this paper was to describe risk factors for VZIG treatment including sources of varicella exposure and to study how many women developed clinical infection and received postpartum vaccination. " 01/11/2021 - "Overall incidence of varicella infection in adults after VARIZIG use was 6%; incidence of varicella infection in children after VARIZIG use was 7%. "
3.	Herpes Zoster 09/01/1992 - "We concluded that Uman-VZIG, both by intralesional and intramuscular administration, is effective and safe in Herpes Zoster treatment." 01/11/2021 - "An open-label, expanded-access program provided VARIZIG to high-risk individuals exposed to varicella or herpes zoster. " 04/01/1989 - "Screening for varicella-zoster immunity and the use of varicella zoster immune globulin in pregnancy." 02/01/1989 - "Physicians can reduce morbidity from these conditions by advising nonimmune pregnant women to avoid exposure to chickenpox and herpes zoster and, when indicated, by promptly administering varicella-zoster immune globulin. " 06/01/1984 - "One of these infants had varicella-zoster antibody when exposed, received varicella-zoster immune globulin, and still had chickenpox develop. "
4.	Neoplasms (Cancer) 09/01/2011 - "Children diagnosed with malignancy in 2009 (serostatus survey) or receiving VZIG between April 2006 and March 2009 (VZIG dispensing study). " 07/08/2022 - "Aciclovir is a safe and effective alternative to VZIG as VZV PEP in children with cancer and should be considered as standard of care." 07/08/2022 - "Prospective multicentre service evaluation of children with cancer who received either VZIG or aciclovir as PEP following significant exposure to varicella zoster virus (VZV) over a 24-month period from May 2018. " 09/01/2011 - "Exposures to VZV result in the administration of PEP to approximately 250 children with cancer annually: half receive an intramuscular injection of VZIG while the remainder receive a course of oral aciclovir. " 01/01/2019 - "PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer."
5.	Pneumonia (Pneumonitis) 12/01/2016 - "The study concludes that few women developed infection after VZIG and none developed pneumonia. " 08/01/2019 - "A novel case of VZV pneumonia in an immunocompromised patient, treated successfully with intravenous VZIG in combination with acyclovir, is reported here." 01/01/1996 - "The objective of this study was to compare the cost-effectiveness of 3 strategies of serologic enzyme-linked immunosorbent assay (ELISA) testing and post-exposure varicella zoster immune globulin (VZIG) prophylaxis for the prevention of maternal varicella pneumonia during pregnancy in patients with negative or uncertain histories of varicella infection. "

Related Drugs and Biologics

1.	Acyclovir (Aciclovir)
2.	varicella-zoster immune globulin (VZIG)
3.	Immunoglobulins (Immunoglobulin)
4.	Intravenous Immunoglobulins (IVIG)
5.	Antibodies
6.	Immunosorbents
7.	Enzymes
8.	Chickenpox Vaccine (Vaccine, Varicella)
9.	Immunoglobulin G (IgG)
10.	Attenuated Vaccines

Related Therapies and Procedures

1.	Therapeutics
2.	Transplantation
3.	Intravenous Administration
4.	Secondary Prevention
5.	Kidney Transplantation