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ursocholic acid
see also records for allocholic and cholic acids
Also Known As:
3 alpha,7 beta,12 alpha-trihydroxy-5 beta-cholan-24-oic acid; 7-epicholic acid
Networked:
8
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Bile Acids and Salts: 11432
Cholic Acids: 14
ursocholic acid: 8
Cholanes
Cholic Acids: 14
ursocholic acid: 8
Related Diseases
1.
Gallstones (Gallstone)
07/01/1991 - "
When 0.25% ursocholic acid or ursodeoxycholic acid was added to the lithogenic diet, the incidence as well as the grade (severity) of the gallstones were reduced.
"
01/01/1989 - "
Ursocholic acid: bile acid and bile lipid dose response and clinical studies in patients with gall stones.
"
07/01/1990 - "
Effect of chronic ursocholic acid administration on bile lipid composition and bile acid pool size in gallstone patients.
"
01/01/1989 - "
The biliary bile acid and bile lipid responses to six weeks treatment with approximately 5, 10, and 15 mg/kg/day of ursocholic acid (UCA) were studied in 11 gall stone patients.
"
04/01/1986 - "
The study included acute duodenal infusion (1 g/h for 5 h) of ursocholic acid contrasted with a less hydrophilic bile acid, ursodeoxycholic acid, in 3 T-tube patients and short-term oral administration (2 wk) of ursocholic acid (10-15 mg/kg X day) to 10 gallstone patients.
"
2.
Cerebrotendinous Xanthomatosis
10/01/1990 - "
Urine from patients with cerebrotendinous xanthomatosis (CTX) was found to contain a number of minor bile acids along with three major bile acids, 7-epicholic acid, norcholic acid, and cholic acid.
"
3.
Liver Diseases (Liver Disease)
05/01/1999 - "
To clarify the relationship between the occurrence of unusual trihydroxy bile acids, namely hyocholic acid, ursocholic acid (UCA), and omega-muricholic acid (omega-MCA) in urine and liver disease severity, urinary bile acids were analyzed by gas-liquid chromatography in acute and late phases of acute hepatitis and before and after ursodeoxycholic acid (UDCA) loading in healthy adults and liver cirrhosis patients.
"
4.
Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
06/01/1997 - "
Ursocholic acid as the free bile acid or as taurine conjugate, although more hydrophilic, is poorly enriched in serum and bile and is ineffective in patients with primary biliary cirrhosis.
"
06/01/1997 - "
Ursocholic acid, a hydrophilic bile acid, fails to improve liver function parameters in primary biliary cirrhosis: comparison with ursodeoxycholic acid.
"
06/01/1997 - "
To compare the effect of short term feeding of ursocholic acid, a hydrophilic bile acid, as the unconjugated acid and the taurine conjugate, on clinical and biochemical features and bile acid metabolism with that of ursodeoxycholic acid in four patients with primary biliary cirrhosis.
"
5.
Liver Cirrhosis (Hepatic Cirrhosis)
05/01/1999 - "
To clarify the relationship between the occurrence of unusual trihydroxy bile acids, namely hyocholic acid, ursocholic acid (UCA), and omega-muricholic acid (omega-MCA) in urine and liver disease severity, urinary bile acids were analyzed by gas-liquid chromatography in acute and late phases of acute hepatitis and before and after ursodeoxycholic acid (UDCA) loading in healthy adults and liver cirrhosis patients.
"
Related Drugs and Biologics
1.
Bile Acids and Salts (Bile Acids)
2.
Ursodeoxycholic Acid (Urso)
3.
Lipids
4.
Acids
5.
Cholic Acid
6.
Taurine
7.
Phospholipids (Phosphatides)
8.
Detergents (Detergent)
9.
Cholesterol
10.
norcholic acid
Related Therapies and Procedures
1.
Oral Administration