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BW 245C

a selective DP receptor agonist

Also Known As:

245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C, (R*,S*)-(+-); BW-245C

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Imidazolidines: 39
        Hydantoins: 306
        BW 245C: 5

Experts

1.	Asano, Koichiro: 1 article (03/2005)
2.	Hirai, Hiroyuki: 1 article (03/2005)
3.	Ikeda, Eiji: 1 article (03/2005)
4.	Ishizaka, Akitoshi: 1 article (03/2005)
5.	Kagyo, Junko: 1 article (03/2005)
6.	Nakajima, Takeshi: 1 article (03/2005)
7.	Niimi, Kyoko: 1 article (03/2005)
8.	Oguma, Tsuyoshi: 1 article (03/2005)
9.	Sayama, Koichi: 1 article (03/2005)
10.	Shiomi, Tetsuya: 1 article (03/2005)

Related Diseases

1.	Hyperalgesia 10/01/1997 - "BW 245C (an agonist for PGD (DP) receptor) blocked the allodynia with an IC50 of 83 ng kg(-1). " 09/01/1996 - "BW 245C, an agonist for PGD2 receptors (DP receptors), but not another DP receptor agonist (ZK 110841) blocked the allodynia similarly. "
2.	Liver Failure 01/01/1986 - "The reported cytoprotective effects of prostaglandins against noxious stimuli in the liver was the basis for the present investigations of the effects of prostacyclin (PGI2) and a prostaglandin analogue (BW 245C) in an animal model of severe liver failure. "
3.	Necrosis 01/01/1986 - "Effect of prostacyclin (PGI2) and a prostaglandin analogue BW 245C on galactosamine-induced hepatic necrosis."
4.	Headache (Headaches) 06/04/1984 - "There was no change in headache or abdominal discomfort scores following either dose of BW 245C . "
5.	Flushing 06/04/1984 - "150 micrograms BW 245C produced significant (p less than 0.05) facial flushing over the period from 15 to 120 minutes after dosing. "

Related Drugs and Biologics

1.	Prostaglandins D
2.	Thromboxane Receptors (Thromboxane Receptor)
3.	Prostaglandin D2
4.	Thromboxanes
5.	Synthetic Prostaglandins (Prostaglandin Analogues)
6.	Epoprostenol (Prostacyclin)
7.	Prostaglandins
8.	Hydantoins
9.	Galactosamine
10.	Acids