|1.||Wang, Zhengtao: 8 articles (04/2015 - 10/2007)|
|2.||Ji, Lili: 7 articles (04/2015 - 10/2007)|
|3.||Stanslas, Johnson: 7 articles (01/2015 - 04/2006)|
|4.||Sheu, Joen-Rong: 6 articles (01/2014 - 12/2011)|
|5.||Lajis, Nordin Haji: 5 articles (10/2014 - 04/2006)|
|6.||Wong, W S Fred: 5 articles (08/2014 - 04/2009)|
|7.||Chen, Jing-Hsien: 5 articles (05/2014 - 08/2008)|
|8.||Lin, Hui-Hsuan: 5 articles (05/2014 - 08/2008)|
|9.||Shen, Han-Ming: 5 articles (03/2014 - 07/2006)|
|10.||Zhou, Jing: 5 articles (03/2014 - 07/2006)|
06/01/2013 - "The preliminary results indicated that the oxidation of C-19-hydroxyl group of andrographolide to corresponding carboxyl group and the subsequent esterification of the formed carboxylic acid led to considerable improvement in cytotoxicity against the cancer cells."
06/01/2015 - "Andrographolide has been shown to have therapeutic potential against various cancers. "
01/01/2013 - "In conclusion, the antiangiogenesis and chemotherapeutic potential of andrographolide may provide a cure for pulmonary tumors in the future. "
12/01/2013 - "Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide."
01/01/2013 - "CY2, CY14 and CY15 for Br, Cl and I substitution respectively), none of the other derivatives showed improved cytotoxicity than andrographolide in the cancer cell lines examined. "
|2.||Body Weight (Weight, Body)
11/01/2014 - "Andrographolide effectively suppressed the respiratory quotient, energy expenditure, and oxygen consumption, which may have contributed to the decreased body-weight gain of the obese mice fed with a HFD. "
08/01/2013 - "NOD mice were randomly divided into four groups and administered with water and andrographolide at 50, 100, and 150mg/kg body weight for four weeks. "
07/01/2009 - "The possible effect of extract of Andrographis paniculata Nees (A paniculata) standardized to >or=10% andrographolide, the main bioactive component, on male fertility in albino Wistar rats was evaluated, by orally administering 0, 20, 200, and 1000 mg/kg of body weight per day, for 65 days prior to mating and 21 days during mating. "
12/01/2008 - "A simple high-performance liquid chromatography (HPLC) method was developed to determine the content of andrographolide (AP) and 14-deoxy-11,12-dideoxyandrographolide (DIAP) in a pooled urine of rat obtained within 24h after an oral dose of Andrographis paniculata leaf extract at 1g/kg body weight. "
09/01/2011 - "wt and the effective dose was found to be 3 mg/kg. We have observed a significant reduction in the ulcer score in rats pretreated with 3 mg of andrographolide/kg body weight. "
10/01/2011 - "Treatment with either l-THP, andrographolide, VPA, or l-THP and andrographolide jointly suppressed myometrial infiltration, improved generalized hyperalgesia, and reduced the amplitude and irregularity of uterine contractions. "
05/01/2012 - "Treatment with andrographolide significantly suppresses the growth of ectopic endometrium in vitro and in vivo, and results in a significant improvement in generalized hyperalgesia in rats with induced endometriosis. "
10/01/2011 - "The retardation of myometrial infiltration, reduction of uterine contractility, and alleviation of generalized hyperalgesia in mice with induced adenomyosis by levo-tetrahydropalmatine (l-THP) and andrographolide."
|4.||Foot and Mouth Disease Hand (Hand, Foot, Mouth Disease)
08/01/2015 - "Andrographolide sulfonate treatment has been shown to improve clinical severe hand, foot, and mouth disease (HFMD) efficacies when combined with conventional therapy. "
08/01/2015 - "Clinical Efficacy of Andrographolide Sulfonate in the Treatment of Severe Hand, Foot, and Mouth Disease (HFMD) is Dependent upon Inhibition of Neutrophil Activation."
01/01/2013 - "Improving the efficacy of conventional therapy by adding andrographolide sulfonate in the treatment of severe hand, foot, and mouth disease: a randomized controlled trial."
01/01/2013 - "Herb-derived compound andrographolide sulfonate (called Xiyanping injection) recommended control measure for severe hand, foot, and mouth disease (HFMD) by the Ministry of Health (China) during the 2010 epidemic. "
10/01/2009 - "In present study, we investigated whether Andrographolide could inhibit allergen-induced airway inflammation and airways hyper-responsiveness and explored the mechanism of Andrographolide on allergen-induced airway inflammation and airways hyper-responsiveness. "
09/01/2014 - "Andrographolide, the major bioactive component of Andrographis paniculata, has been demonstrated to have various biological properties including anti-inflammation, antioxidation, and anti-hepatotoxicity. "
01/01/2014 - "Andrographolide is the most active and critical constituent isolated from the leaves of Andrographis paniculata, a herbal medicine widely used for treating anti-inflammation in Asia. "
01/01/2013 - "The purpose of our investigation was designed to reveal the effect of andrographolide on various aspects of LPS induced inflammation in vivo and in vitro. "
11/28/2011 - "Inhibition of TNF-α-Induced Inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway."
|2.||Adenosine Diphosphate (ADP)
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||p38 Mitogen-Activated Protein Kinases
|2.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|4.||Heterologous Transplantation (Xenotransplantation)